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Figure 5 | BMC Genetics

Figure 5

From: Mutations in genes involved in nonsense mediated decay ameliorate the phenotype of sel-12 mutants with amber stop mutations in Caenorhabditis elegans

Figure 5

The nature of the smg-1(by146) mutation. A) The structure of the smg-1 gene with the position of the primers, GN1212, GN1213 and GN1264 used to detect and genotype the by146 mutation. The gene structure was captured from Wormbase http://www.wormbase.org/ Wormbase release WS187). Below the gene structure the position of AvaII and DdeI restriction sites are shown by vertical bars along with the approximate position of the by146 mutation by a horizontal bar. B) The domains within the SMG-1 protein according to [40] along with the expected affect of the by146 mutation on the protein. NLS = Nuclear Localization Signal, FAT = FRAP, ATM, and TRRAP domain, PIK domain = phosphatidylinositol kinase (PIK) domain and FATC = FAT carboxyl terminus domain.

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BMC Genomic Data

ISSN: 2730-6844

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