Papillation pattern in strains that contain one or two copies of the duplication marker ura3::HIS3. Ura-His+ strains were grown overnight in YPD rich medium. 106 and 104 cells from each culture were spotted to plates containing selective media lacking uracil (-ura) or uracil and histidine (-ura, -his). Papillae were scored after 3 days. The strains shown are KAY579 (haploid), KAY626 (hemizygous diploid), and KAY625 (homozygous diploid).