Table 2 VKORC1 mutations and polymorphisms found in Mus musculus from different geographic areas in Germany and from Terceira, Azores.
Geographic area | Amino acid substitutions | No. of samples | Silent mutations |
|---|---|---|---|
Berlin | Glu37Gly | 12 | -- |
Lower Saxony | Glu37Gly | 1 | -- |
Westphalia | Arg58Gly | 13 | -- |
Arg12Trp, Ala26Ser, Ala48Thr, Arg58Gly, Arg61Leu | 7 | Glu37Glu | |
Arg12Trp, Ala26Ser, Ala48Thr, Arg61Leu | 2 | Glu37Glu | |
Rhineland | Leu128Ser | 17 | -- |
Tyr139Cys | 1 | -- | |
Azores | Tyr139Cys | 1 | -- |