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Table 2 QTL for spontaneous home-cage activity

From: QTL analyses of temporal and intensity components of home-cage activity in KJR and C57BL/6J strains

QTL Chr. Markers (position (cM)) Trait LOD EA ED Contribution
(%)
   Proximal Distal      
Hylaq1 2 D2Mit126 (48.5) D2Mit423 (69.1) THA 5.4* 8.6 × 103 5.3 × 103 4.5
     AT 7.5* 1.5 × 103 0 11.9
     AA 3.7* 1.2 2.9 2.5
Hylaq2 2 D2Mit22 (73.4) D2Mit29 (92.3) THA 6.8* 12.4 × 103 3.3 × 103 8.9
     AT 7.2* 1.7 × 103 -0.2 × 103 15.2
     AA 5.0* 2.2 2.4 3.6
Hylaq3 10 D10Mit73 (48.6) D10Mit180 (56.2) THA 7.9* 13.5 × 103 0.4 × 103 9.5
     AT 3.4 1.1 × 103 0 6.4
     AA 7.1* 4.0 1.0 7.3
  1. QTLs for spontaneous home-cage activity are shown. Markers indicate flanking microsatellite markers located at just outside of one LOD support interval of the peaks for AT or THA. Position indicates genetic distances from centromere to marker in a scale of cM. The marker positions were obtained from the genetic distance calculated by the recombination frequency of B6xKJR F2. The peak LOD score at Hylaq1 and Hylaq2 were calculated by QTL Cartographer. Asterisks indicate significant QTLs which were above scores obtained by permutation tests (THA: 3.6, AT: 3.7 AA: 3.6). EA and ED indicate the additive effect and dominance effect, respectively, that were calculated by QTL Cartographer. Contribution were calculated by phenotypic variance at the peak of each QTL (V P = E A 2/2 + E D 2/4) divided by total phenotypic variance (VT) in B6xKJR F2.