A strong association of axillary osmidrosis with the wet earwax type determined by genotyping of the ABCC11 gene

Table 1 Association of AO with the wet earwax type

Subject studied	Genotype at the rs17822931 locus (earwax phenotype)
	GG	GA	(wet type)	AA	(dry type)	total
Individuals with AO (Kyushu)	5	73	(78)^a	1	(1)^a	79
General habitants in Kyushu	6	51	(57)^a	104	(104)^a	161
total			(135)^a		(105)^a	240
Individuals with AO (Okinawa)	3	34	(37)^b	1	(1)^b	38
General habitants in Okinawa	2	15	(17)^b	17	(17)^b	34
total			(54)^b		(18)^b	72
Individuals with AO (Nagasai)	2	39	(41)^c	0	(0)^c	41
General habitants in Nagasaki	4	36	(40)^c	87	(87)^c	127
total			(81)^c		(87)^c	168

^ap < 1.1 × 10^-24, ^bp < 3.0 × 10^-6, ^cp < 8.4 × 10^-17: all comparisons were performed under a dominant model. All statistical analyses were done by Fisher's exact test. Hardy-Weinberg equilibrium was supported under the observed allele frequency in control samples by Exact Hardy-Weinberg test (p-value > 0.1) [18]. These comparisons were performed using plink software [19]http://pngu.mgh.harvard.edu/purcell/plink/.

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