Table 2 Summary of average maximum LOD scores and average IC using the baseline marker subset from step 1 for the 9 study designs with ungenotyped parents.

From: Handling linkage disequilibrium in qualitative trait linkage analysis using dense SNPs: a two-step strategy

Number of Sibs	MLS (SD)	Average IC
2 Affected	9.62 (2.75)	0.72
3 Affected	14.01 (3.43)	0.80
4 Affected	5.02 (1.95)	0.85
2 Affected + 1 Unaffected	8.66 (2.49)	0.80
3 Affected + 1 Unaffected	5.41 (2.12)	0.85
4 Affected + 1 Unaffected	3.17 (1.55)	0.88
2 Affected + 2 Unaffected	4.41 (1.80)	0.85
3 Affected + 2 Unaffected	3.18 (1.57)	0.88
4 Affected + 2 Unaffected	1.89 (1.29)	0.90

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