2 affected sibs | 3 affected sibs | 4 affected sibs | ||||||
---|---|---|---|---|---|---|---|---|
Method | LD threshold | Ave # SNPs | MLS (SD) | IC | MLS (SD) | IC | MLS (SD) | IC |
Unadjusted | 3713 | 9.62 (2.75) | 0.72 | 14.01 (3.43) | 0.80 | 5.02 (1.95) | 0.85 | |
MT | 8snp1cM | 480 | 1.20 (0.96) | 0.72 | 1.34 (1.01) | 0.80 | 0.36 (0.47) | 0.85 |
MT | 4snp1cM | 259 | 0.65 (0.67) | 0.71 | 0.60 (0.63) | 0.80 | 0.22 (0.36) | 0.85 |
MT | 2snp1cM | 135 | 0.66 (0.68) | 0.67 | 0.76 (0.74) | 0.79 | 0.26 (0.38) | 0.84 |
MT | 1snp1cM | 68 | 0.76 (0.73) | 0.61 | 1.05 (0.88) | 0.76 | 0.34 (0.47) | 0.83 |
RE | 0.7 | 409 | 0.44 (0.53) | 0.73 | 0.54 (0.61) | 0.80 | 0.2 (0.33) | 0.85 |
RE | 0.5 | 309 | 0.37 (0.50) | 0.72 | 0.45 (0.55) | 0.80 | 0.18 (0.34) | 0.85 |
RE | 0.3 | 200 | 0.43 (0.54) | 0.7 | 0.58 (0.60) | 0.80 | 0.23 (0.39) | 0.85 |
RE | 0.1 | 62 | 0.73 (0.73) | 0.61 | 1.18 (0.96) | 0.76 | 0.44 (0.57) | 0.83 |
SNPLINK | 0.7 | 531 | 0.65 (0.78) | 0.73 | 0.66 (0.79) | 0.80 | 0.3 (0.46) | 0.85 |
SNPLINK | 0.5 | 401 | 0.75 (0.81) | 0.72 | 0.73 (0.83) | 0.80 | 0.31 (0.46) | 0.85 |
SNPLINK | 0.3 | 287 | 0.85 (0.88) | 0.71 | 0.81 (0.84) | 0.80 | 0.33 (0.47) | 0.85 |
SNPLINK | 0.1 | 120 | 0.65 (0.74) | 0.64 | 0.70 (0.81) | 0.77 | 0.31 (0.46) | 0.83 |