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Figure 2 | BMC Genetics

Figure 2

From: Determining the effectiveness of High Resolution Melting analysis for SNP genotyping and mutation scanning at the TP53 locus

Figure 2

Genotyping using spike-in control DNA to distinguish common homozygotes from rare homozygotes. A. The melting curves of AG heterozygotes (in red) are distinguished from homozygous AA (in grey). Homozygous GG samples (in blue) are not distinguished from the common AA homozygous samples.B After spike-in of a homozygous AA sample, the GG samples are converted into AG heterozygotes (in blue), and they are now distinguished from AA samples.

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ISSN: 2730-6844

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