Figure 1

Forward stepwise selection of informative individuals and the corresponding increase in using real and simulated data. To gain information efficiently forward stepwise selection of the most informative individuals is employed for maximizing the power of global test T, for the real hipROA data (upper panels: n(case) = 61 and n(control) = 653) and a comparable simulated data (lower panels: n(case) = n(control) = 500). (i) The left panels: The points represent the selection by . The groups in the y-labels are ordered as in Table 3: the upper part 1HH, HHH, H1H, HH1 represents the selection order for cases, and the lower part selection order H1H, HH1, 1HH, HHH for controls using the real data. Consequently, the jumps between the groups, and cases and controls are caused by using different methods. (ii) The right panels show the increase in by resolving phase uncertainty.