BMC Genomic Data

Table 4 Type I error of global test via 1500 simulations at α = 0.05

From: Regression-based approach for testing the association between multi-region haplotype configuration and complex trait

Sample Size	Minor Allele Frequency	Model Type
		Model 1	Model 2	Model 5	Model 6
50	q = 0.1	0.034(0.024-0.047)	0.031(0.021-0.044)	0.048(0.036-0.063)	0.039(0.028-0.053)
	q = 0.3	0.050(0.037-0.065)	0.041(0.030-0.055)	0.044(0.032-0.059)	0.044(0.032-0.059)
	q = 0.5	0.052(0.039-0.068)	0.062(0.048-0.079)	0.047(0.035-0.062)	0.056(0.043-0.072)
100	q = 0.1	0.040(0.029-0.054)	0.032(0.022-0.045)	0.047(0.035-0.062)	0.037(0.026-0.051)
	q = 0.3	0.038(0.027-0.052)	0.044(0.032-0.059)	0.043(0.031-0.059)	0.037(0.026-0.051)
	q = 0.5	0.048(0.036-0.063)	0.044(0.032-0.059)	0.051(0.038-0.067)	0.052(0.039-0.068)
200	q = 0.1	0.045(0.033-0.060)	0.041(0.030-0.055)	0.055(0.042-0.071)	0.031(0.021-0.044)
	q = 0.3	0.048(0.036-0.063)	0.041(0.030-0.055)	0.047(0.035-0.062)	0.042(0.030-0.056)
	q = 0.5	0.047(0.035-0.062)	0.049(0.036-0.064)	0.037(0.026-0.051)	0.041(0.030-0.055)
400	q = 0.1	0.027(0.018-0.039)	0.040(0.029-0.054)	0.042(0.030-0.056)	0.038(0.027-0.052)
	q = 0.3	0.043(0.031-0.059)	0.037(0.026-0.051)	0.041(0.030-0.055)	0.044(0.032-0.059)
	q = 0.5	0.041(0.030-0.055)	0.052(0.039-0.068)	0.042(0.030-0.056)	0.048(0.036-0.063)

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