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Table 1 haplotyping accuracy for the different compared methods

From: A genetic algorithm based method for stringent haplotyping of family data

Haplotyping method and data

correct haplotype (%)

haplotype

errors (%)

unresolved

cases (%)

AIL pedigree

   

   GA- 0.95

95.10

0.20

4.80

   GA- 0.5

97.10

2.60

0.15

   Hapsim 1

96.70

3.30

0.00

   Merlin 2

83.00

1.80

14.20

QTL-MAS pedigree

   

   GA- 0.95

87.00

0.05

13.00

   GA- 0.5

90.00

1.00

9.00

   Hapsim 1

97.00

3.00

0.00

   Merlin 2

95.00

1.30

3.70

  1. We compare three methods: our GA based method with high stringency (0.95), and low stringency (0.50), a deterministic method, and a likelihood based descent tree (Merlin), The results are given in percent of the non obvious heterozygous markers (non homozygous parents).
  2. 1Hernández-Sánchez and Knott (2009) [7]
  3. 2Abecasis et al (2002)[12]