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Figure 4 | BMC Genetics

Figure 4

From: Characterization of the chromosomal inversion associated with the Koa mutation in the mouse revealed the cause of skeletal abnormalities

Figure 4

Schematic diagram of recombinant chromosomes resulting from crossover between overlapping regions of Koa and Eh inversions. The Eh +/+ Koa double heterozygote has both Koa type and Eh type chromosomes. If crossover occurred in the overlapping region of the two inversions (C region), recombinant chromosomes with duplication of the B region and deletion of the D region (DupB-DelD), or with deletion of the B region and duplication of the D region (DelB-DupD), were transmitted to the offspring. The phenotypes of mice with these chromosomes are indicated at the bottom.

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