Hypermethylation of the DLC1 CpG island does not alter gene expression in canine lymphoma

BMC Genomic Data

Table 1 Demographic data of dogs in the study

Patient #	Sex	Breed	Age	BW	B/T	Stage	Survival	Diagnosis
1	FS	Am Co Sp	13	14.5	B	IV	706	Lymphoma
2	FS	Affenpinscher	12	5.6	T	IV	14	DSLL
3	MC	Mix	5	11.7	B	IV	52*	DLCL
4	FS	Mix	11	30.4	B	IV	104	DLCL
5	MC	Engl Spring	6	22.7	B	III	605	DLCL
6	MC	Mix	8	22.7	B	IV	238	DLCL
7	FS	Mix	7	22.5	B	IV	458	LBL
8	MC	Lab	6	43.7	B	III	448	DLCL
9	MC	Staff Terr	10	34.8	B	IV	6	FL II
10	MC	Mix	12	28.1	B	IV	754@	DLCL
11	FS	Schnauzer	11	10	B	N/A	231	Lymphoma
12	FS	Welsh Corgi	7	17.7	B	V	972@	DLCL
13	MC	Blue Tick	7	34.1	B	III	266	LBL
14	MC	Collie	5	32.2	T	II	97	Lymphoma
15	FS	Engl Spring	5	25.7	B	V	352	FL III
16	MC	Rottweiler	5	36	B	V	684	Burkitt
17	MC	Am Co Sp	8	15.2	B	IV	324	Lymphoma
18	MC	Golden	5	48.4	B	III	128	DLCL
19	FS	Beagle	9	11.6	B	V	140	DLCL
20	FS	Mix	5	17.5	B	V	427	DLCL
21	FS	Golden	5	34.2	B	IV	270	Lymphoma

Abbreviated breeds include American cocker spaniel (Am Co Sp), English springer spaniel (Engl Spring), Staffordshire terrier (Staff Terr), Blue tick hound (Blue Tick), Golden retriever (Golden) and mixed-breed dogs (Mix). Age is listed in years. Body weight is listed in kilograms. The immunophenotype (B/T) is listed. The stage is according to the World Health Organization staging standards. Survival is listed in days. Survival times marked with "@" to denote dogs alive at final analysis or lost to follow-up. Diagnosis is listed according to the Working Formulation where the tissue blocks could be retrieved or as lymphoma where they could not. Abbreviations for the diagnoses are as follows: DSLL, diffuse small lymphocytic lymphoma; DLCL, diffuse large cell lymphoma; LBL, lymphoblastic lymphoma; FL II, follicular lymphoma II; FL III, follicular lymphoma III.

ISSN: 2730-6844