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Table 5 Epistatic model - recessive (EPI RR).

From: Neural networks for modeling gene-gene interactions in association studies

 

Low risk

High risk

 

r = 5

r = 10

Theoretical penetrance matrix

Neural network

  

   Mean absolute difference E

   Sum

0.2071

0.1410

Logistic regression

  

   Mean absolute difference E

   Sum

0.4849

0.6150

Logistic regression (design variables)

  

   Mean absolute difference E

   Sum

0.3503

0.2755

  1. Mean absolute differences between theoretical and estimated penetrance matrices from 100 replications in the low and high risk scenario.