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Table 9 MDR analyses: selected variables and identification as redundant or synergistic behavior.

From: Neural networks for modeling gene-gene interactions in association studies

  

MDR analyses

  

Redundant

Synergistic

 

Two-locus disease model

Risk scenario

Only A

Only B

Both

Only A

Only B

Both

ADD

low

 

82

18

   

100

 

high

 

7

93

   

100

HET

low

 

68

32

   

100

 

high

1

6

93

   

100

MULT

low

 

7

93

   

100

 

high

  

100

   

100

EPI RR

low

10

22

39

2

4

23

100

 

high

18

17

59

1

2

3

100

EPI DD

low

  

12

 

1

87

100

 

high

  

18

  

82

100

EPI RD

low

63

 

34

  

3

100

 

high

97

 

3

   

100

  1. Bold numbers mark the mode of the selected variables in the low and high risk scenario.