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Figure 1 | BMC Genetics

Figure 1

From: A single mutation results in diploid gamete formation and parthenogenesis in a Drosophila yemanuclein-alpha meiosis I defective mutant

Figure 1

Sequence conservation of the domain that contains V478E yem1 mutation(YD1). The V478 containing domain was subjected to a Blast search and Yem-alpha like sequences were aligned with CLUSTAL-W (Panel A). The alignment was optimized with BioEdit. Grey and black shadings highlight similar and identical residues respectively using a 60% consensus. To the exception of Yem-alpha and Ubn1 the other sequences are putative proteins, Yem-alpha being the archetypal sequence published long before the human orthologue [14, 22]. Accession numbers are given in Additional file 1, Table S1. Panel B is a schematic representation of the YD1 domain of Ubn1 and Yem-alpha. Yem-alpha DNA binding properties have been determined experimentally [14]. The nucleotide sequence of the Ubn1 DNA binding domain was previously reported as "VT4 cDNA" (Additional file 1, Table S1).

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