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Table 1 The results of sib-TDT model analysis using the large family sample set.

From: A 2cM genome-wide scan of European Holstein cattle affected by classical BSE

  

Location

 

unadjusted

permuted

 

SNP ID

CHR

bp

Gene

p value

p value

Bonferroni

AAFC02065030

2

37,055,124

 

1.93E-08

3.61E-05

5.45E-05

rs29020694

4

90,418,076

 

1.87E-06

4.05E-03

5.29E-03

AAFC02132123_1

4

117,126,683

LOC100138299

9.38E-07

1.98E-03

2.65E-03

AAFC02132123_2

4

117,126,810

LOC100138299

3.38E-06

7.33E-03

9.55E-03

AAFC02012009

5

30,554,866

LOC507184

3.53E-06

7.69E-03

9.98E-03

rs29003193

5

66,501,993

 

3.12E-08

5.79E-05

8.82E-05

rs29012226

5

67,701,052

ANKS1B

6.63E-07

1.38E-03

1.87E-03

SCAFFOLD106936

6

98,767,642

 

6.35E-07

1.32E-03

1.80E-03

rs29016161

7

24,604,791

 

2.45E-06

5.31E-03

6.93E-03

rs29017305

9

62,946,258

BACH2

2.30E-06

4.97E-03

6.49E-03

rs29013631

10

38,725,566

 

2.25E-06

4.87E-03

6.36E-03

rs29022366

12

80,076,729

LOC786668

2.74E-06

5.95E-03

7.75E-03

rs29010388

14

4,145,186

 

4.20E-07

8.56E-04

1.19E-03

AAFC02138417

15

70,632,844

 

3.31E-06

7.19E-03

9.36E-03

rs29010371

16

63,558,950

FAM129A

1.06E-06

2.26E-03

3.00E-03

rs29009572

17#

37,575,810

 

1.29E-06

2.76E-03

3.65E-03

rs29021871

17

44,213,230

 

1.06E-06

2.25E-03

2.99E-03

CART

20#

4,922,252

CART

3.57E-08

6.75E-05

1.01E-04

rs29018531

20

38,814,738

 

1.32E-06

2.82E-03

3.72E-03

AAFC02028192

21

5,702,403

MEF2A

1.24E-07

2.49E-04

3.49E-04

rs29022862

21

12,595,937

 

1.85E-07

3.73E-04

5.22E-04

rs29009825

21

24,827,395

 

1.90E-06

4.11E-03

5.38E-03

rs29012664

22

42,415,179

FHIT

5.30E-07

1.10E-03

1.50E-03

NW_930303_1

24#

29,286,364

 

1.02E-07

2.05E-04

2.90E-04

NW_930303_2

24#

29,286,314

 

3.06E-07

6.17E-04

8.64E-04

SCAFFOLD176855

28

26,871,628

SLC29A3

1.03E-06

2.18E-03

2.90E-03

SCAFFOLD68962

X

7,641,750

 

3.15E-06

6.86 E-03

8.91E-03

  1. Locations were determined by blast to bovine sequence version 4.0. All other locations denoted by # were either determined from bovine sequence version 2.0, 4.1 or the Maryland sequence assembly. Permuted p values reported here are from a 10,000,000 genome-wide SNP permutation.