Polymorphisms in the gene encoding bovine interleukin-10 receptor alpha are associated with Mycobacterium avium ssp. paratuberculosis infection status

Table 1 Characteristics of SNPs discovered in IL10, IL10RA/B, TGFB1, and SLC11A1.

Gene	SNP	dbSNP ssID	Region	Mutation	Primer set (5'-3')
IL10	-30A > C	ss104807640	5'		F: GGTAAAGCAGTCCTGAATCCAA
					R: TCCTTCATGGGCCCTATTT
	-285T > C	ss104807641	5'		F: AGCCAGCAGCTCTCAAAGTC
					R: GTGTTCAGTGTGGTCCTGGAT
IL10RA	633C > A	ss104807642	Coding	Syn	F: TCGTGTTTATTGCTCTGGTTGT
					R: CCTGCTTCCTTCCCTCCT
	984G > A^a	ss104807643	Coding	Syn	F: GGGTTCCTGCTGGTGACTC
					R: GCCAATGCCACTGTCCTC
	1098C > T^a	ss104807644	Coding	Syn	F: GGGTTCCTGCTGGTGACTC
					R: GCCAATGCCACTGTCCTC
	1185C > T	ss104807645	Coding	Syn	F: AGTGCAGACAGCGGGATCT
					R: TTCTTCAGGGGTCTGCAAAG
	1269T > C^a	ss104807646	Coding	Syn	F: AGTGCAGACAGCGGGATCT
					R: TTCTTCAGGGGTCTGCAAAG
	1302A > G^a	ss104807647	Coding	Syn	F: AGTGCAGACAGCGGGATCT
					R: TTCTTCAGGGGTCTGCAAAG
IL10RB	503C > T^b	ss104807648	Coding	Non	F: GGGAATTCAGGGAATAAAGCA
					R: CTGTTTGGGGAATGCAGATT
	569A > G^b	ss104807649	Coding	Non	F: GGGAATTCAGGGAATAAAGCA
					R: CTGTTTGGGGAATGCAGATT
TGFB1	258C > T	ss104807650	Coding	Syn	F: CCCTTGCCAAACACTGACA
					R: CCTAGCCCAGGCCACTTT
SLC11A1	650C > T	ss104807654	Coding	Non	F: TCCTCTGGAGAAGGGAAAGG
					R: ATTCAGAGGCAGGAGTCGAG
	1066C > G	ss104807655	Coding	Non	F: ACATGTGTTGGCCAAGTGAA
					R: ACATCCGAGTCCTGAGTGGT

ISSN: 2730-6844