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Table 3 Haplotype frequencies in the 3' coding region of IL10RA and their association with MAP-infection status.

From: Polymorphisms in the gene encoding bovine interleukin-10 receptor alpha are associated with Mycobacterium avium ssp. paratuberculosis infection status

IL10RA haplotype

Frequency

   
   

MAP infection status

   

633C > A

984G > A

1185C > T

Negative (n = 235)

Positive (n = 180)

β ± SE

OR (95% CI)

Contrast ± SE

A

G

C

52.6%

60.6%

0.35 ± 0.15 *

1.42 (1.06-1.90)

 

A

A

T

27.2%

20.8%

-0.37 ± 0.17 *

0.69 (0.49-0.97)

-0.45 ± 0.18 **

C

A

C

19.1%

17.8%

-0.09 ± 0.18

0.92 (0.65-1.30)

-0.23 ± 0.19

A

A

C

1.1%

0.8%

-0.25 ± 0.74

0.78 (0.18-3.31)

-0.47 ± 0.74

  1. β ± SE, haplotype effect ± standard error; OR (95% CI), odds ratio (95% confidence interval); contrast ± SE, haplotype contrast ± standard error against the most frequent haplotype, AGC.
  2. * Comparison-wise significance at 5% probability level from logistic regression of haplotype counts against infection status.
  3. * * Experimental-wise significance at 5% probability level from logistic regression and Bonferroni's correction for multiple hypothesis testing.
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BMC Genomic Data

ISSN: 2730-6844

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