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Table 1 Comparison of expected and observed values for F S T

From: Influence of mutation rate on estimators of genetic differentiation - lessons from Arabidopsis thaliana

Forward simulations

m

E( F ST )

O( F ST )

O(Φ ST )

O( F' ST )

O( D )

0.1

0.0045

0.0040

0.0049

0.0190

0.0148

0.01

0.0431

0.0440

0.0414

0.1920

0.1549

0.001

0.3104

0.3104

0.3067

0.7581

0.6492

0.0001

0.8182

0.7570

0.7667

0.9831

0.9307

0.00001

0.9783

0.8339

0.8500

0.9931

0.9580

Coalescent simulations

m

E( F ST )

O(SNP F ST )

O(MSAT Φ ST )

O(DNA Φ ST )

0.1

0.0023

0.0277

0.0287

0.0299

0.01

0.0220

0.0400

0.0420

0.0488

0.001

0.1837

0.2057

0.2003

0.2127

0.0001

0.6923

0.6950

0.7124

0.6933

  1. Expected F ST was calculated as described in the methods, observed values are the simulation means for the different estimators or marker types. For the coalescent simulations MSAT means microsatellite markers and DNA means DNA sequence haplotypes. Simulation values are shown for a single mutation rate, μ = 0.00001.