From: How old is this mutation? - a study of three Ashkenazi Jewish founder mutations
Method - Markers | Estimated mutation age (generations) | Estimated mutation age including correction for growth with r = 1.5 | 95% credible interval (DMLE) or 95% confidence interval (Goldgar) |
---|---|---|---|
Single marker results - median of 10 markers2 | 59.22 | 69.01 | Â |
Single marker results - median of 6 markers3 | 35.76 | 42.27 | Â |
DMLE with growth rate r = 1.5 | N/A | 16.84 | [12.75, 22.45] |
Goldgar method | 11 | 17.623 | Without growth [6, 20] With growth [13.62, 26.62]4 |