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Table 3 Significant haplotypes of markers at the ITGA11 gene region associated with tick burden

From: Haplotypes that include the integrin alpha 11 gene are associated with tick burden in cattle

SNP1

Code

Sample2

N03

N1

N2

R2 4

α5

SE6

p-value

10snp

h10

110111111 - 0

DTE

(48)

605

17

0

0.0146

-0.738

0.243

0.0025

10snp

h19

111000111 - 0

DTE

(48)

582

38

2

0.0131

-0.432

0.151

0.0043

10snp

h23

111010101 - 0

BRM

(24)

419

4

0

0.0422

2.119

0.492

2 × 10-5^

4,5,6

h7

- - - 010 - - - - -

DTE

(8)

808

23

1

0.0082

-0.507

0.194

0.0092

  

BRM

(5)

477

8

0

0.0386

1.542

0.350

1 × 10-5^

6,7,8

h1

- - - - - 001 - - -

DTE

(7)

891

124

10

0.0125

-0.297

0.083

0.0003^

7,8,9

h2

- - - - - - 011 - -

DTE

(7)

734

156

0

0.0077

-0.231

0.088

0.0087

7,8,9

h7

- - - - - - 101 - -

BRM

(5)

476

42

2

0.0128

0.380

0.147

0.0099^

8,9,10

h2

- - - - - - - 011 -

BRM

(3)

477

42

2

0.0128

0.381

0.147

0.0097^

8,9,10

h5

- - - - - - - 111 -

BRM

(3)

6

98

417

0.0183

-0.310

0.100

0.0020^

8,9,11

h2

- - - - - - - 10 - 1

BRM

(5)

513

5

0

0.0261

1.651

0.444

0.0002^

8,9,11

h3

- - - - - - - 11 - 0

DTE

(6)

538

332

8

0.0117

-0.212

0.066

0.0013^

  

BRM

(5)

8

102

408

0.0150

-0.269

0.096

0.0053^

9,10,11

h2

- - - - - - - - 011

BRM

(5)

537

5

0

0.0233

1.596

0.444

0.0004^

  1. 1 SNP markers used to generate the haplotypes (4- rs29025981, 5- rs41594962, 6- ss161109814, 7- ss161109807, 8- ss161109797, 9- rs29023635, 10- rs29023639, 11- rs29014770) and haplotype number.
  2. 2 DTE - dairy tick experiment, BRM - Brahman and number of haplotypes reconstructed.
  3. 3 N0 number of animals with zero copies of the haplotype, N1 number of animals with one copy of the haplotype, N2 number of animals with two copies of the haplotype.
  4. 4 Proportion of residual variance explained by the common haplotype.
  5. 5 Haplotype substitution effect in phenotypic standard deviations (tick count for the DTE and tick score for BRM).
  6. 6 Standard error of α.
  7. ^ Significant after Bonferroni correction.