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Table 1 Performance of PCA-BCIT at level 0.05 with strategies 1-3†

From: PCA-based bootstrap confidence interval tests for gene-disease association involving multiple SNPs

Sample size

Type I error

Power

 

1

2

3

1

2

3

100

0.014

0.036

0.037

0.156

0.163

0.176

200

0.016

0.044

0.036

0.249

0.278

0.292

300

0.017

0.028

0.029

0.383

0.426

0.368

400

0.014

0.04

0.02

0.508

0.485

0.516

500

0.009

0.035

0.042

0.613

0.595

0.597

600

0.006

0.032

0.042

0.677

0.662

0.683

700

0.007

0.061

0.04

0.733

0.758

0.73

800

0.004

0.043

0.045

0.801

0.791

0.819

900

0.005

0.057

0.051

0.826

0.855

0.858

1000

0.01

0.056

0.05

0.871

0.901

0.889

  1. † 1 case-only extracting strategy (CAES), 2 control-only extracting strategy (COES), 3 case-control extracting strategy (CES)
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BMC Genomic Data

ISSN: 2730-6844

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