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Table 3 Allele substitution effect (standard error in parenthesis) between the 8 SNPs and survival in the herd, reproduction and calving performance

From: Association of bovine leptin polymorphisms with energy output and energy storage traits in progeny tested Holstein-Friesian dairy cattle sires

SNP Allele Survival in the herd (%) Calving interval (days) Direct calving difficulty (%) Maternal calving difficulty (%) Gestation length (days) Calf Perinatal mortality (%)
Number of bulls   477 501 575 506 614 201
LEPR-T945M C to T -0.2833 (0.2395) 0.20 (0.44) 0.26 (0.20) 0.08 (0.25) -0.06 (0.13) -0.06 (0.16)
LEP-2470 C to T -0.1036 (0.2060) 0.19 (0.37) -0.02 (0.17) 0.11 (0.21) -0.05 (0.11) 0.30 (0.13)*
LEP-1457 A to G 0.2072 (0.1290) -0.07 (0.23) -0.11 (0.12) -0.07 (0.13) -0.11 (0.07) -0.12 (0.08)
LEP-1238 C to G -0.2009 (0.1361) 0.07 (0.25) 0.24 (0.12)† -0.12 (0.14) 0.16 (0.08)* 0.16 (0.09) †
LEP-963 C to T 0.1737 (0.1333) -0.05 (0.24) -0.30 (0.12)* 0.2 (0.14) -0.17 (0.08)* -0.14 (0.09)
Y7F A to T -0.1500 (0.3342) 0.11 (0.60) -0.22 (0.28) 0.25 (0.33) -0.33 (0.18) † 0.10 (0.23)
R25C C to T 0.1550 (0.1348) 0.03 (0.24) -0.28 (0.12)* 0.16 (0.14) -0.18 (0.08)* -0.10 (0.09)
A80V C to T -0.3049 (0.1476)* 0.29 (0.27) 0.11 (0.13) 0.00 (0.15) 0.05 (0.08) 0.08 (0.10)
  1. Significance of difference from zero = P < 0.10; * = P < 0.05; ** = P < 0.01
  2. Because of complete linkage disequilibrium between phases among the SNPs LEP-1457, LEP-1609 and LEP-580, only LEP-1457 was retained for the association analysis