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Table 4 Allele substitution effect (standard error in parenthesis) between the 8 SNPs and milk production

From: Association of bovine leptin polymorphisms with energy output and energy storage traits in progeny tested Holstein-Friesian dairy cattle sires

SNP

Allele

Milk yield (kg)

Fat yield (kg)

Protein yield (kg)

Fat percent (%)

Protein percent (%)

SCS (logeunits)

Number of bulls

 

742

742

742

742

742

703

LEPR-T945M

C to T

-21.49 (16.8)

-0.53 (0.60)

-0.60 (0.47)

0.0067 (0.0127)

0.0033 (0.0062)

0.0009 (0.0114)

LEP-2470

C to T

23.61 (14.29)†

0.05 (0.51)

0.20 (0.40)

-0.0172 (0.0108)

-0.0114 (0.0052)*

0.0006 (0.0096)

LEP-1457

A to G

-7.73 (9.16)

0.16 (0.32)

0.00 (0.25)

0.0072 (0.0069)

0.0045 (0.0033)

-0.0097 (0.0061)

LEP-1238

C to G

14.57 (9.87)

-0.38 (0.35)

0.03 (0.27)

-0.0159 (0.0073)*

-0.0080 (0.0035)*

0.0106 (0.0065)†

LEP-963

C to T

-16.29 (9.62)†

0.27 (0.34)

-0.15 (0.27)

0.0154 (0.0072)*

0.0073 (0.0035)*

-0.0079 (0.0064)

Y7F

A to T

-39.19 (22.70)†

-1.11 (0.80)

-1.25 (0.63)*

0.0056 (0.0170)

-0.0007 (0.0083)

-0.0152 (0.0153)

R25C

C to T

-13.32 (9.61)

0.36 (0.34)

-0.07 (0.27)

0.0152 (0.0072)*

0.0071 (0.0035)*

-0.0100 (0.0064)

A80V

C to T

7.97 (10.55)

-0.12 (0.38)

0.21 (0.29)

-0.0073 (0.0079)

-0.0009 (0.0039)

0.0105 (0.0070)

  1. Significance of difference from zero † = P < 0.10; * = P < 0.05
  2. Because of complete linkage disequilibrium between phases among the SNPs LEP-1457, LEP-1609 and LEP-580, only LEP-1457 was retained for the association analysis