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Table 4 Allele substitution effect (standard error in parenthesis) between the 8 SNPs and milk production

From: Association of bovine leptin polymorphisms with energy output and energy storage traits in progeny tested Holstein-Friesian dairy cattle sires

SNP Allele Milk yield (kg) Fat yield (kg) Protein yield (kg) Fat percent (%) Protein percent (%) SCS (logeunits)
Number of bulls   742 742 742 742 742 703
LEPR-T945M C to T -21.49 (16.8) -0.53 (0.60) -0.60 (0.47) 0.0067 (0.0127) 0.0033 (0.0062) 0.0009 (0.0114)
LEP-2470 C to T 23.61 (14.29) 0.05 (0.51) 0.20 (0.40) -0.0172 (0.0108) -0.0114 (0.0052)* 0.0006 (0.0096)
LEP-1457 A to G -7.73 (9.16) 0.16 (0.32) 0.00 (0.25) 0.0072 (0.0069) 0.0045 (0.0033) -0.0097 (0.0061)
LEP-1238 C to G 14.57 (9.87) -0.38 (0.35) 0.03 (0.27) -0.0159 (0.0073)* -0.0080 (0.0035)* 0.0106 (0.0065)
LEP-963 C to T -16.29 (9.62) 0.27 (0.34) -0.15 (0.27) 0.0154 (0.0072)* 0.0073 (0.0035)* -0.0079 (0.0064)
Y7F A to T -39.19 (22.70) -1.11 (0.80) -1.25 (0.63)* 0.0056 (0.0170) -0.0007 (0.0083) -0.0152 (0.0153)
R25C C to T -13.32 (9.61) 0.36 (0.34) -0.07 (0.27) 0.0152 (0.0072)* 0.0071 (0.0035)* -0.0100 (0.0064)
A80V C to T 7.97 (10.55) -0.12 (0.38) 0.21 (0.29) -0.0073 (0.0079) -0.0009 (0.0039) 0.0105 (0.0070)
  1. Significance of difference from zero = P < 0.10; * = P < 0.05
  2. Because of complete linkage disequilibrium between phases among the SNPs LEP-1457, LEP-1609 and LEP-580, only LEP-1457 was retained for the association analysis