Genetic maps of TRD. (A) Percent transmission of A alleles when fit to a single-locus model at rs8260829 on Chr 7. (B) Percent transmission of S alleles when fit to a single-locus model at rs4228380 on Chr 10. (C) Percent transmission of S alleles when fit to a single-locus model at rs13481119 on Chr 11. Open circles represent the distortion observed. Darkened squares represent the level of distortion expected with a single distorting locus positioned at the maximally distorted marker on each chromosome. Red lines indicate maximal likely location of the TRD causing alleles. The observed recombination distances are indicated on the x-axis and only markers showing distortion are represented.