TY - JOUR AU - Burr, G. O. AU - Burr, M. M. AU - Miller, E. S. PY - 1932 DA - 1932// TI - On the fatty acids essential in nutrition. III JO - J Biol Chem VL - 97 ID - Burr1932 ER - TY - JOUR AU - Steinberg, G. AU - Slaton, W. H. AU - Howton, D. R. AU - Mead, J. F. PY - 1956 DA - 1956// TI - Metabolism of essential fatty acids: IV. Incorporation of linoleate into arachidonic acid JO - J Biol Chem VL - 220 ID - Steinberg1956 ER - TY - JOUR AU - Mead, J. F. AU - Steinberg, G. AU - Howton, D. R. PY - 1953 DA - 1953// TI - Metabolism of essential fatty acids: Incorporation of acetate into arachidonic acid JO - J Biol Chem VL - 205 ID - Mead1953 ER - TY - CHAP AU - Mead, J. F. AU - Howton, D. R. PY - 1957 DA - 1957// TI - Metabolism of essential fatty acids: VII. Conversion of γ-linolenic acid to arachidonic acid BT - J Biol Chem ID - Mead1957 ER - TY - JOUR AU - Nakamura, M. T. AU - Nara, T. Y. PY - 2004 DA - 2004// TI - Structure, function, and dietary regulation of delta6, delta5, and delta9 desaturases JO - Annu Rev Nutr VL - 24 UR - https://doi.org/10.1146/annurev.nutr.24.121803.063211 DO - 10.1146/annurev.nutr.24.121803.063211 ID - Nakamura2004 ER - TY - JOUR AU - Das, U. N. PY - 2006 DA - 2006// TI - Essential fatty acids: biochemistry, physiology and pathology JO - Biotechnol J VL - 1 UR - https://doi.org/10.1002/biot.200600012 DO - 10.1002/biot.200600012 ID - Das2006 ER - TY - JOUR AU - Schmitz, G. AU - Ecker, J. PY - 2008 DA - 2008// TI - The opposing effects of n-3 and n-6 fatty acids JO - Prog Lipid Res VL - 47 UR - https://doi.org/10.1016/j.plipres.2007.12.004 DO - 10.1016/j.plipres.2007.12.004 ID - Schmitz2008 ER - TY - JOUR AU - Simopoulos, A. P. PY - 2008 DA - 2008// TI - The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases JO - Exp Biol Med (Maywood) VL - 233 UR - https://doi.org/10.3181/0711-MR-311 DO - 10.3181/0711-MR-311 ID - Simopoulos2008 ER - TY - JOUR AU - Martinez, M. PY - 1992 DA - 1992// TI - Tissue levels of polyunsaturated fatty acids during early human development JO - J Pediatr VL - 120 UR - https://doi.org/10.1016/S0022-3476(05)81247-8 DO - 10.1016/S0022-3476(05)81247-8 ID - Martinez1992 ER - TY - JOUR AU - Cordain, L. AU - Eaton, S. B. AU - Sebastian, A. AU - Mann, N. AU - Lindeberg, S. AU - Watkins, B. A. AU - O'Keefe, J. H. AU - Brand-Miller, J. PY - 2005 DA - 2005// TI - Origins and evolution of the Western diet: health implications for the 21st century JO - Am J Clin Nutr VL - 81 ID - Cordain2005 ER - TY - JOUR AU - Burdge, G. C. PY - 2006 DA - 2006// TI - Metabolism of alpha-linolenic acid in humans JO - Prostaglandins Leukot Essent Fatty Acids VL - 75 UR - https://doi.org/10.1016/j.plefa.2006.05.013 DO - 10.1016/j.plefa.2006.05.013 ID - Burdge2006 ER - TY - JOUR AU - Pawlosky, R. J. AU - Lin, Y. H. AU - Llanos, A. AU - Mena, P. AU - Uauy, R. AU - Salem, N. PY - 2006 DA - 2006// TI - Compartmental analyses of plasma 13C- and 2H-labeled n-6 fatty acids arising from oral administrations of 13C-U-18:2n-6 and 2H5-20:3n-6 in newborn infants JO - Pediatr Res VL - 60 UR - https://doi.org/10.1203/01.pdr.0000232782.09352.ef DO - 10.1203/01.pdr.0000232782.09352.ef ID - Pawlosky2006 ER - TY - JOUR AU - Emken, E. A. AU - Adlof, R. O. AU - Gulley, R. M. PY - 1994 DA - 1994// TI - Dietary linoleic acid influences desaturation and acylation of deuterium-labeled linoleic and linolenic acids in young adult males JO - Biochim Biophys Acta VL - 1213 UR - https://doi.org/10.1016/0005-2760(94)00054-9 DO - 10.1016/0005-2760(94)00054-9 ID - Emken1994 ER - TY - JOUR AU - Malerba, G. AU - Schaeffer, L. AU - Xumerle, L. AU - Klopp, N. AU - Trabetti, E. AU - Biscuola, M. AU - Cavallari, U. AU - Galavotti, R. AU - Martinelli, N. AU - Guarini, P. PY - 2008 DA - 2008// TI - SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease JO - Lipids VL - 43 UR - https://doi.org/10.1007/s11745-008-3158-5 DO - 10.1007/s11745-008-3158-5 ID - Malerba2008 ER - TY - JOUR AU - Xie, L. AU - Innis, S. M. PY - 2008 DA - 2008// TI - Genetic variants of the FADS1 FADS2 gene cluster are associated with altered (n-6) and (n-3) essential fatty acids in plasma and erythrocyte phospholipids in women during pregnancy and in breast milk during lactation JO - J Nutr VL - 138 UR - https://doi.org/10.3945/jn.108.096156 DO - 10.3945/jn.108.096156 ID - Xie2008 ER - TY - JOUR AU - Schaeffer, L. AU - Gohlke, H. AU - Muller, M. AU - Heid, I. M. AU - Palmer, L. J. AU - Kompauer, I. AU - Demmelmair, H. AU - Illig, T. AU - Koletzko, B. AU - Heinrich, J. PY - 2006 DA - 2006// TI - Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids JO - Hum Mol Genet VL - 15 UR - https://doi.org/10.1093/hmg/ddl117 DO - 10.1093/hmg/ddl117 ID - Schaeffer2006 ER - TY - JOUR AU - Martinelli, N. AU - Girelli, D. AU - Malerba, G. AU - Guarini, P. AU - Illig, T. AU - Trabetti, E. AU - Sandri, M. AU - Friso, S. AU - Pizzolo, F. AU - Schaeffer, L. PY - 2008 DA - 2008// TI - FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease JO - Am J Clin Nutr VL - 88 ID - Martinelli2008 ER - TY - JOUR AU - Rzehak, P. AU - Heinrich, J. AU - Klopp, N. AU - Schaeffer, L. AU - Hoff, S. AU - Wolfram, G. AU - Illig, T. AU - Linseisen, J. PY - 2009 DA - 2009// TI - Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 ( FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes JO - Br J Nutr VL - 101 UR - https://doi.org/10.1017/S0007114508992564 DO - 10.1017/S0007114508992564 ID - Rzehak2009 ER - TY - JOUR AU - Marquardt, A. AU - Stohr, H. AU - White, K. AU - Weber, B. H. PY - 2000 DA - 2000// TI - cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family JO - Genomics VL - 66 UR - https://doi.org/10.1006/geno.2000.6196 DO - 10.1006/geno.2000.6196 ID - Marquardt2000 ER - TY - JOUR AU - Lattka, E. AU - Illig, T. AU - Heinrich, J. AU - Koletzko, B. PY - 2009 DA - 2009// TI - FADS gene cluster polymorphisms: important modulators of fatty acid levels and their impact on atopic diseases JO - J Nutrigenet Nutrigenomics VL - 2 UR - https://doi.org/10.1159/000235559 DO - 10.1159/000235559 ID - Lattka2009 ER - TY - JOUR AU - Tanaka, T. AU - Shen, J. AU - Abecasis, G. R. AU - Kisialiou, A. AU - Ordovas, J. M. AU - Guralnik, J. M. AU - Singleton, A. AU - Bandinelli, S. AU - Cherubini, A. AU - Arnett, D. PY - 2009 DA - 2009// TI - Genome-wide association study of plasma polyunsaturated fatty acids in the InCHIANTI Study JO - PLoS Genet VL - 5 UR - https://doi.org/10.1371/journal.pgen.1000338 DO - 10.1371/journal.pgen.1000338 ID - Tanaka2009 ER - TY - JOUR AU - Horrobin, D. F. AU - Ells, K. AU - Morse-Fisher, N. AU - Manku, M. S. PY - 1991 DA - 1991// TI - Fatty acid distribution in plasma phospholipids in normal individuals from different geographical locations JO - J Nutr Environ Med VL - 2 UR - https://doi.org/10.3109/13590849109084122 DO - 10.3109/13590849109084122 ID - Horrobin1991 ER - TY - STD TI - Lattka E, Eggers S, Moeller G, Heim K, Weber M, Mehta D, Prokisch H, Illig T, Adamski J: A common FADS2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1. J Lipid Res. 51 (1): 182-191. ID - ref23 ER - TY - JOUR AU - Barnes, K. C. AU - Grant, A. V. AU - Hansel, N. N. AU - Gao, P. AU - Dunston, G. M. PY - 2007 DA - 2007// TI - African Americans with asthma: genetic insights JO - Proc Am Thorac Soc VL - 4 UR - https://doi.org/10.1513/pats.200607-146JG DO - 10.1513/pats.200607-146JG ID - Barnes2007 ER - TY - JOUR AU - Khera, A. AU - McGuire, D. K. AU - Murphy, S. A. AU - Stanek, H. G. AU - Das, S. R. AU - Vongpatanasin, W. AU - Wians, F. H. AU - Grundy, S. M. AU - de Lemos, J. A. PY - 2005 DA - 2005// TI - Race and gender differences in C-reactive protein levels JO - J Am Coll Cardiol VL - 46 UR - https://doi.org/10.1016/j.jacc.2005.04.051 DO - 10.1016/j.jacc.2005.04.051 ID - Khera2005 ER - TY - JOUR AU - Albert, M. A. AU - Glynn, R. J. AU - Buring, J. AU - Ridker, P. M. PY - 2004 DA - 2004// TI - C-reactive protein levels among women of various ethnic groups living in the United States (from the Women's Health Study) JO - Am J Cardiol VL - 93 UR - https://doi.org/10.1016/j.amjcard.2004.01.067 DO - 10.1016/j.amjcard.2004.01.067 ID - Albert2004 ER - TY - JOUR AU - Bray, P. F. AU - Mathias, R. A. AU - Faraday, N. AU - Yanek, L. R. AU - Fallin, M. D. AU - Herrera-Galeano, J. E. AU - Wilson, A. F. AU - Becker, L. C. AU - Becker, D. M. PY - 2007 DA - 2007// TI - Heritability of platelet function in families with premature coronary artery disease JO - J Thromb Haemost VL - 5 UR - https://doi.org/10.1111/j.1538-7836.2007.02618.x DO - 10.1111/j.1538-7836.2007.02618.x ID - Bray2007 ER - TY - JOUR AU - Bowden, D. W. AU - Lehtinen, A. B. AU - Ziegler, J. T. AU - Rudock, M. E. AU - Xu, J. AU - Wagenknecht, L. E. AU - Herrington, D. M. AU - Rich, S. S. AU - Freedman, B. I. AU - Carr, J. J. PY - 2008 DA - 2008// TI - Genetic epidemiology of subclinical cardiovascular disease in the diabetes heart study JO - Ann Hum Genet VL - 72 UR - https://doi.org/10.1111/j.1469-1809.2008.00446.x DO - 10.1111/j.1469-1809.2008.00446.x ID - Bowden2008 ER - TY - JOUR AU - Metcalfe, L. D. AU - Schmitz, A. A. AU - Pelka, J. R. PY - 1966 DA - 1966// TI - Rapid preparation of fatty acid esters from lipids for gas chromatographic analysis JO - Anal Chem VL - 38 UR - https://doi.org/10.1021/ac60235a044 DO - 10.1021/ac60235a044 ID - Metcalfe1966 ER - TY - JOUR AU - Weaver, K. L. AU - Ivester, P. AU - Seeds, M. AU - Case, L. D. AU - Arm, J. P. AU - Chilton, F. H. PY - 2009 DA - 2009// TI - Effect of dietary fatty acids on inflammatory gene expression in healthy humans JO - J Biol Chem VL - 284 UR - https://doi.org/10.1074/jbc.M109.004861 DO - 10.1074/jbc.M109.004861 ID - Weaver2009 ER - TY - JOUR AU - Purcell, S. AU - Neale, B. AU - Todd-Brown, K. AU - Thomas, L. AU - Ferreira, M. A. AU - Bender, D. AU - Maller, J. AU - Sklar, P. AU - de Bakker, P. I. AU - Daly, M. J. PY - 2007 DA - 2007// TI - PLINK: a tool set for whole-genome association and population-based linkage analyses JO - Am J Hum Genet VL - 81 UR - https://doi.org/10.1086/519795 DO - 10.1086/519795 ID - Purcell2007 ER - TY - JOUR AU - Buetow, K. H. AU - Edmonson, M. AU - MacDonald, R. AU - Clifford, R. AU - Yip, P. AU - Kelley, J. AU - Little, D. P. AU - Strausberg, R. AU - Koester, H. AU - Cantor, C. R. PY - 2001 DA - 2001// TI - High-throughput development and characterization of a genomewide collection of gene-based single nucleotide polymorphism markers by chip-based matrix-assisted laser desorption/ionization time-of-flight mass spectrometry JO - Proc Natl Acad Sci USA VL - 98 UR - https://doi.org/10.1073/pnas.98.2.581 DO - 10.1073/pnas.98.2.581 ID - Buetow2001 ER - TY - JOUR AU - Zeger, S. L. AU - Liang, K. Y. PY - 1986 DA - 1986// TI - Longitudinal data analysis for discrete and continuous outcomes JO - Biometrics VL - 42 UR - https://doi.org/10.2307/2531248 DO - 10.2307/2531248 ID - Zeger1986 ER - TY - JOUR AU - Price, A. L. AU - Patterson, N. J. AU - Plenge, R. M. AU - Weinblatt, M. E. AU - Shadick, N. A. AU - Reich, D. PY - 2006 DA - 2006// TI - Principal components analysis corrects for stratification in genome-wide association studies JO - Nat Genet VL - 38 UR - https://doi.org/10.1038/ng1847 DO - 10.1038/ng1847 ID - Price2006 ER - TY - JOUR AU - Barrett, J. C. AU - Fry, B. AU - Maller, J. AU - Daly, M. J. PY - 2005 DA - 2005// TI - Haploview: analysis and visualization of LD and haplotype maps JO - Bioinformatics VL - 21 UR - https://doi.org/10.1093/bioinformatics/bth457 DO - 10.1093/bioinformatics/bth457 ID - Barrett2005 ER - TY - JOUR AU - Gabriel, S. B. AU - Schaffner, S. F. AU - Nguyen, H. AU - Moore, J. M. AU - Roy, J. AU - Blumenstiel, B. AU - Higgins, J. AU - DeFelice, M. AU - Lochner, A. AU - Faggart, M. PY - 2002 DA - 2002// TI - The structure of haplotype blocks in the human genome JO - Science VL - 296 UR - https://doi.org/10.1126/science.1069424 DO - 10.1126/science.1069424 ID - Gabriel2002 ER -