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Table 2 The performances of single-locus test, PCA-LRT and KPCA-LRT

From: Gene- or region-based association study via kernel principal component analysis

Region

# of SNPs

Physical location

Gene involved

Results

    

Single**

PCA

KPCA

Region 1

12

114030646-114132504

PTPN22

2.30E-8*

4.63E-9*

3.14E-9*

Region 2

8

143025126-143050638

ANKRD35

1.94E-6*

0.837

4.25E-6*

Region 3

13

156523590-156572131

DUSP23

2.47E-4

6.01E-3

7.82E-6*

Region 4

15

19880889-19929909

RNF186

2.05E-4

5.33E-6*

2.54E-6*

  1. *significant at the level of 1E-5
  2. **the most significant p value in the corresponding region
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BMC Genomic Data

ISSN: 2730-6844

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