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Table 1 Estimated parameters of the QTL identified by GLMM compared to true values in the simulation.

From: Generalized linear mixed model for segregation distortion analysis

 

True effect

True proportion

Estimate

StdErr

Position (cM)

LOD

Proportion

QTL 1

1.4135

0.1543

1.1905

0.1357

50

16.6828

0.1224

QTL 2

-0.9993

0.0771

-0.8296

0.1252

125

9.5271

0.0594

QTL 3

0.9993

0.0771

0.9605

0.1328

360

11.3536

0.0796

QTL 4

-1.2048

0.1121

-1.1991

0.1353

905

17.0304

0.1241

QTL 5

1.0000

0.0772

0.8593

0.1310

1735a

9.3347

0.0637

QTL 6

-1.41354

0.1543

-1.2959

0.1380

2115

19.1230

0.1450

Co-factor 1

1.0000

0.1545

1.0217

0.1020

--

21.7673

0.1803

Co-factor 2

1.0000

0.0386

1.1007

0.1809

--

8.0412

0.0523

  

0.8455b

    

0.8272c

  1. a1735 The true location is 1750 cM and the estimated location is 15 cM away from the true location.
  2. b0.8455 This is the true (total) proportion of the liability variance contributed by the six QTL and the two co-factors.
  3. c0.8272 This is the estimated (total) proportion of the liability variance contributed by the six QTL and the two co-factors.