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Table 4 Directionality for multigenic traits where the parental strains differed significantly

From: Genetic divergence and the genetic architecture of complex traits in chromosome substitution strains of mice

CSS panel No. QTLs “away from” donor “towards” donor
Overall “more extreme“ than donor
A/J 342 7.3% (25) 92.7% (317) 1.8% (6)
PWD 122 31.3% (38) 68.9% (84) 12.3% (15)
MSM 168 11.9% (20) 88.1% (148) 0% (0)
  1. “Towards donor” and “away from” means that a CSS shifted towards or away from the phenotype of the donor strain. “More extreme than donor” means that a CSS not only shifted the phenotype towards but also significantly beyond phenotype of the donor strain. Number of QTLs is provided in parentheses. The analysis was restricted to multigenic traits where the parental strains also differed significantly.