Figure 3

Analysis of homozygosity/heterozygosity for cSNPs, based on the idea that severely damaging variants are less likely to be homozygous. H.S: human synonymous cSNPs; M.S: macaque synonymous cSNPs; H.B: human nsSNPs predicted to be “benign” by PolyPhen; M.B: macaque nsSNPs predicted to be “benign” by PolyPhen; H.D: human nsSNPs predicted to be damaging by PolyPhen; M.D: macaque nsSNPs predicted to be damaging by PolyPhen.