Noa | Gb | Tc | ACRd | Definition | Mode of calculation |
---|---|---|---|---|---|
1 | NRk | NRk | WIC | Total weeks sampled | Total number of weeks sampled over the entire challenge period, according to batch number |
2 | Pe | L | STR | Total observed parasitemia detections | Total number of observed weekly positive parasitemia detections over entire challenge period. |
3 | Pe | L | STRTV | Total observed T. vivax detections | Total number of observed positive T. vivax detections over entire challenge period. |
4 | Pe | L | STRTC | Total observed T. congolense detections | Total number of observed positive T congolense detections over entire challenge period. |
5 | Pe | L | TPS | Sum of parasitemic scores | Sum of all parasitemic scores over the entire challenge period |
6 | Pe | L | MPAR | Mean parasitemic score | TPS/STR |
7 | Pe | L | %PARD | Percentage of weeks animal parasitemic | 100*STR/WIC |
8 | Pe | L | NINF | Number of infection cycles | Total number of infection cycles, defined as number of new infections following initial exposure or treatment. |
9 | Tf | L | NT | Number of treatments | Total number of treatments. If after first treatment PCV was still <18%, the animal was given a second treatment and this was counted as two treatments. |
10 | Tf | L | NT1 | Number of treatments when PCV <18% | Total No. of treatments given when PCV <18% |
11 | Tf | H | NIT | Proportion of non-treated parasitemia detections | (STR-NT)/STR |
12 | Tf | L | MNT | Mean treatments per week | NT/WIC |
13 | Tf | L | MNTI | Mean treatments per week when PCV<18% | NT1/WIC |
14 | IC1,g | H | DF1 | Days from exposure to first infection | No. of days from date animal is first exposed to tsetse challenge to date of first parasitemia detection |
15 | IC1,g | H | DT1 | Days from first infection to first treatment for that infection | No. of days from date of first parasitemia detection to date of first treatment for that infection (in some cases a second treatment was needed to control the infection). |
16 | IC1,g | H | DC1A | Length of first infection cycle, counting from exposure to treatment | DF1+DT1; This is length of first infection cycle counting from exposure to treatment. |
17 | IC1,g | H | DF2 | Days from first treatment to second infection | No. of days from date animal is first treated for first infection to date of second parasitemia detection (i.e., first parasitemia detection after final treatment for first infection). |
18 | IC1,g | H | DC1B | Length of first infection cycle counting from first infection | DT1+DF2; This is length of first infection cycle counting from first infection to second infection (after treatment for first infection). |
19 | IC1,g | H | DT2 | Days from second infection to treatment for that infection | No of days from second parasitemia detection to first treatment for that infection. |
20 | IC1,g | H | DC2A | Length of second infection cycle, counting from first treatment for first infection to first treatment for second infection. | DF2+DT2 |
21 | IC1,g | H | DC12 | Total length of first two infection cycles counting from exposure through first treatment for second infection. | DF1+DT1+DF2+DT2 = DC1A+DC2A |
22 | PCh | NRk | PCI | Initial PCV | Mean PCV of animal before challenge |
23 | PCh | H | MPC | Mean PCV | Mean PCV of animal during the entire challenge period |
24 | PCh | H | MXPC | Maximum PCV | Maximum PCV of animal during the entire challenge period |
25 | PCh | H | MNPC | Minimum PCV | Minimum PCV of animal during the entire challenge period |
26 | PCh | H | PCSR | PCV at first screening | PCV of animal when first screened |
27 | PCh | H | PCF1 | PCV at first infection | PCV of animal at first parasitemic detection |
28 | PCh | H | PCT1 | PCV at the first treatment | PCV of animal when first treated after first detection of parasitemia |
29 | PCh | H | PCF2 | PCV at the second infection | PCV of animal when infected for second time |
30 | PCh | H | PCT2 | PCV at second treatment | PCV of animal when treated after second infection |
31 | PCh | H2 | PCIF1 | PCV change from before exposure to PCV at first infection | PCF1-PCI |
32 | PCh | H2 | PCF1T1 | PCV change from first infection to PCV at first treatment | PCT1-PCF1 |
33 | PCh | H2 | PCIT1 | PCV change from before exposure to PCV at first treatment | PCT1-PCI |
34 | PCh | L,H3 | PCT1F2 | PCV change from first treatment to second infection | PCF2- PCT1 |
35 | WTi | NRk,4 | WTI | Initial body weight | Mean of body weight of animal before challenge (within a month before exposure) |
36 | WTi | NRk,4 | MWT | Mean body weight | Mean of body weight of animal during entire challenge period |
37 | WTi | NRk,4 | MXWT | Maximum body weight | Maximum body weight during the entire challenge period |
38 | WTi | NRk,4 | MNWT | Minimum body weight | Minimum body weight during the entire challenge period |
39 | WTi | NRk,4 | WTF1 | Body weight at time of first infection | Body weight of animal at time of first parasitemia detection after initial exposure |
40 | WTi | NRk,4 | WTT1 | Body weight at first treatment | Body weight of animal at first treatment |
41 | WTi | NRk,4 | WTF2 | Body weight at second infection | Body weight of animal at second infection (i.e., at first parasitemia detection after first treatment) |
42 | WTi | NRk,4 | WTE | Body weight at end of challenge period | Body weight of the animal in the last month of tsetse challenge period |
43 | WTCj | H2 | WTIF1 | Body weight change from initial body weight to first infection | WTF1 - WTI |
44 | WTCj | H2 | WTIT1 | Body weight change from initial body weight to weight at first treatment | WTT1 - WTI |
45 | WTCj | NRk,4 | WTC | Mean Body weight change during challenge period | MWT - WTI |
46 | WTCj | NRk,4 | WTC-W | Mean Body weight change per week during challenge | (WTC)/WIC |
47 | WTCj | H2 | WTF1T1 | Body weight change from first infection to first treatment | WTT1 – WTF1 |
48 | WTCj | H2 | WTT1F2 | Body weight change from first treatment to second infection | WTF2 - WTT1 |
49 | WTCj | H | WT1E | Body weight changefrom start to end of challenge period | WTE – WT1 |