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Table 6 Comparisons of the haplotype diversity of GSTM cluster in populations of Tver, Murom, Kursk and HapMap populations (CEU, CHB, JPT, YRI) *

From: Analysis of DNA variations in GSTA and GSTMgene clusters based on the results of genome-wide data from three Russian populations taken as an example

  MUROM KURSK СЕU CHB JPT YRI Number of haploblock The level of significance
TVER 0,5078 0,5183 0,2862 0,0021 <0,0001 0,4485 I 0,0025
  0,3202 0,8943 0,2160 <0,0001 <0,0001 <0,0001 II 0,0019
  0,9120 0,9206 0,7647 <0,0001 <0,0001 <0,0001 III 0,0025
MUROM   0,6541 0,3994 0,0027 <0,0001 0,5856 I 0,0025
   0,4052 0,1369 <0,0001 <0,0001 <0,0001 II 0,0019
   0,9392 0,5527 <0,0001 <0,0001 <0,0001 III 0,0025
KURSK    0,0811 0,0313 0,0018 0,1701 I 0,0025
    0,0906 <0,0001 <0,0001 <0,0001 II 0,0019
    0,8592 <0,0001 <0,0001 <0,0001 III 0,0025
  1. * Pairwise P-values are presented. The last column contains Bonferroni adjusted P-values calculated for each block. The calculations was performed using the formula P = 0.05/ ([n × a] – 1), where “n” is the number of haplotypes and “a” is the number of populations [16].