Body composition and gene expression QTL mapping in mice reveals imprinting and interaction effects

Cheng, Ye; Rachagani, Satyanarayana; Cánovas, Angela; Mayes, Mary Sue; Tait, Richard G; Dekkers, Jack CM; Reecy, James M

doi:10.1186/1471-2156-14-103

BMC Genomic Data

Table 4 Statistics of QTL that interact with sex

From: Body composition and gene expression QTL mapping in mice reveals imprinting and interaction effects

			Position	Flanking markers^c		am + dm + im^d		am + dm^e		am^f
Chr	Trait^a	Groups	(cM)^b	Left	Right	P-value	%var	P-value	% var	P-value	% var
1	Soleus	pQTL	19	rs3696088	rs13472794	1.57E-06	2.94	3.28E-01	0.23	5.05E-01	0.05
1	Pec	pQTL	23	rs3696088	rs13472794	1.23E-03	1.45	5.64E-03	0.95	7.01E-04	1.07
1	Edl	pQTL	89	rs3666905	rs13476312	1.65E-02	1.03	3.48E-01	0.21	1.68E-01	0.19
2	P	tQTL	34	rs6268714	rs13476554	1.18E-02	1.53	3.73E-03	1.55	2.04E-01	0.23
3	Pec	pQTL	36	rs13477132	rs13477174	1.90E-02	0.99	8.37E-02	0.50	2.39E-02	0.51
3	Edl	pQTL	64	rs3663873	rs13477430	4.79E-02	0.80	2.09E-02	0.78	4.70E-01	0.05
6	EGF	eQTL	32	rs13478839	rs4226048	4.18E-03	1.79	2.08E-03	1.67	4.85E-04	1.64
6	Fat	pQTL	10	petM-02094-1	rs3678887	3.61E-02	0.86	2.06E-02	0.78	3.46E-01	0.09
6	AI	pQTL	11	petM-02094-1	rs3678887	6.05E-02	0.73	3.85E-02	0.65	5.31E-01	0.04
7	Pec	pQTL	47	rs3676254	rs3656205	5.61E-03	1.25	2.84E-03	1.16	3.39E-03	0.85
9	Fat	pQTL	15	rs3719607	rs8259427	2.31E-02	0.95	1.02E-02	0.92	4.53E-01	0.06
9	AI	pQTL	15	rs3719607	rs8259427	3.50E-02	0.85	1.61E-02	0.82	5.38E-01	0.04
11	AI	pQTL	14	rs6276300	rs6199956	3.29E-02	0.87	4.53E-02	0.62	4.35E-02	0.41
11	Fat	pQTL	15	rs6276300	rs6199956	3.75E-02	0.85	4.80E-02	0.61	3.65E-02	0.44
11	Gastro	pQTL	24	rs6276300	rs6199956	3.00E-04	1.90	1.77E-04	1.74	3.23E-05	1.74
11	BMI	pQTL	49	rs13481054	rs3701609	1.44E-01	0.54	6.64E-02	0.54	2.85E-02	0.48
14	BMI	pQTL	65	rs3709178	rs13482404	1.54E-02	1.03	1.16E-01	0.43	5.64E-01	0.03
17	Gastro	pQTL	11	rs13482893	rs3719497	1.15E-01	0.59	5.29E-02	0.59	1.67E-02	0.57
17	AI	pQTL	13	rs13482893	rs3719497	5.86E-02	0.73	2.56E-02	0.72	4.15E-02	0.41
17	Fat	pQTL	13	rs13482893	rs3719498	4.83E-02	0.78	2.11E-02	0.77	4.19E-02	0.41

^aTrait abbreviations are the same as in Table 1. P: total protein.
^bPeak position of QTL detected in Kosambi centimorgans.
^cFlanking markers (left and right) of the QTL peak. See Additional file 1: Table S6 for marker information.
^dam + dm + im tested the overall interaction, which included additive, dominance, and imprinted pQTL by sex interactions. P-value < 0.05 is shown in italics %var: percentage of phenotypic variance accounted for at QTL position.
^eam + dm tested for non-imprinted interactions, which included additive and dominance pQTL by sex interactions. P-value < 0.05 is shown in italics %var: percentage of phenotypic variance accounted for at QTL position.
^fam tested the additive interaction, which included additive pQTL by sex interactions. P-value < 0.05 is shown in italics %var: percentage of phenotypic variance accounted for at QTL position.

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