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Table 1 Characteristics of the selected SNPs

From: Impact of obesity-related genes in Spanish population

Locus GENE name HGN SNP TAG-SNP CHR position HGVS names HORTEGA GEN% PIZARRA GEN% HORTEGA MAF PIZARRA MAF HWE p-value (All/controls)
1p31.1 NEURONAL GROWTH REGULATOR 1 NEGR1 rs3101336   72523773 NT_032977.8:g.42723104C > T 96.80 100 0.237 0.252 0.472/0.663
rs2568958   72537704 NT_032977.8:g.42737035A > G 98.86 100 0.115 0.095 0.858/0.303
rs2815752   72585028 NT_032977.8:g.42784359A > G 98.93 100 0.355 0.349 0.929/0.304
1q25.2 SEC16 HOMOLOG B (S. CEREVISIAE) SEC16B rs10913469   176180142 NM_033127.2:c.1881 + 177A > G 97.80 100 0.154 0.143 0.293/1
2q14.1 INSULIN INDUCED GENE 2 INSIG2 rs7566605   118552495 NT_022135.15:g.7543947C > G 98.20 99.77 0.454 0.439 0.706/0.643
2p25.3 TRANSMEMBRANE PROTEIN 18 TMEM18 rs2867125   612827 NT_022327.14:g.612827T > C 97.47 100 0.351 0.397 0.078/0.186
rs6548238   624905 NT_022327.14:g.624905T > C 98.93 99.88 0.449 0.419 0.043/0.141
rs4854344   628144 NT_022327.14:g.628144G > T 98.73 99.88 0.380 0.387 0.0521/0.164
3q27 ADIPONECTIN, C1Q AND COLLAGEN DOMAIN ADIPOQ rs17300539   188042154 NT_005612.15:g.93054610G > A 98.53 99.54 0.433 0.403 0.032/0.342
rs3774261 1 188054253 NM_004797.2:c.215-414A > G 98.20 99.54 0.496 0.484 0.967/0.726
3q28 ETS VARIANT 5 ETV5 rs7647305   187316984   95 98.85 0.118 0.125 0.902/0.655
4p13 GLUCOSAMINE-6-PHOSPHATE DEAMINASE 2 GNPDA2 rs10938397   44877284 NT_006238.10:g.4884493A > G 97.80 100 0.195 0.198 0.382/0.340
5q31-q32 ADRENERGIC, BETA-2-, RECEPTOR, SURFACE ADRB2 rs12654778 1 148185934 NT_029289.10:g.9368677G > A 98.13 100 0.363 0.330 0.207/0.318
6p22.2-p21.3 PROLACTIN PRL rs4712652   22186594 NT_007592.14:g.12936866G > A 97.07 97.58 0.346 0.375 0.804/0.516
10p12 PHOSPHOTRIESTERASE RELATED PTER rs10508503   16339957 NT_077569.2:g.10662847C > T 96.27 99.19 0.346 0.375 0.006/0.015
11p13 BRAIN-DERIVED NEUROTROPHIC FACTOR BDNF rs4923461   27613486 NR_002832.1:c.244-4482G > A 98.33 99.88 0.169 0.172 0.955/0.637
rs925946   27623778 NR_002832.1:c.404 + 5650G > T 98.47 100 0.347 0.375 0.0001/0.003
rs10501087   27626684 NR_002832.1:c.404 + 8556G > T 98.00 99.65 0.424 0.384 0.779/0.634
rs6265   27636492 NM_001709.3:c.196G > A (p.V66M) 98.13 100 0.461 0.489 0.373/0.426
11p14.1 BDNF OPPOSITE STRAND (NON-PROTEIN CODING) BDNFOS rs4074134   27603861 NR_002832.1:c.244-14107G > C 98.86 99.54 0.185 0.160 0.956/0.841
11p11.2 MITOCHONDRIAL CARRIER HOMOLOG 2 MTCH2 rs4752856 1 47604618 NM_014342.2:c.681 + 590C > T 98.40 99.77 0.240 0.261 0.928/0.699
rs10838738   47619625 NM_014342.2:c.87 + 882T > C 97.87 99.65 0.489 0.455 1/0.545
12q13 FAS APOPTOTIC INHIBITORY MOLECULE 2 FAIM2 rs7138803   48533735 NT_029419.11:g.12390774G > A 98.66 99.42 0.354 0.344 0.391/0.111
16p11 ATAXIN 2-LIKE ATXN2L rs8049439   28745016 NM_007245.2:c.466-46T > C 96.53 100 0.327 0.356 0.619/0.512
16q12.2 FAT MASS AND OBESITY ASSOCIATED FTO rs6499640   52327178 NM_001080432.1:c.45 + 31536A > G 98.07 99.88 0.173 0.173 0.694/0.488
rs1421085 1 52358455 NM_001080432.1:c.46-43098T > C 97.87 100 0.237 0.261 1/0.719
rs1121980 1 52366748 NM_001080432.1:c.46-34805G > A 98.93 100 0.073 0.092 0.617/0.389
rs8050136 1 52373776 NM_001080432.1:c.46-27777C > A 98.86 99.19 0.220 0.228 0.420/0.470
rs3751812   52375961 NM_001080432.1:c.46-25592G > T 98.80 100 0.381 0.376 0.471/0.471
rs9939609 1 52378028 NM_001080432.1:c.46-23525T > A 98.33 99.88 0.174 0.170 0.966/0.876
rs7190492   52386253 NM_001080432.1:c.46-15300G > A 98.73 99.65 0.351 0.351 0.782/0.438
rs8044769   52396636 NM_001080432.1:c.46-4917C > T 97.33 100 0.339 0.329 0.967/0.880
16q22-q23 V-MAF MUSCULOAPONEUROTIC FIBROSARCOMA MAF rs1424233   78240252   99.13 99.77 0.321 0.321 0.805/0.52
16p11.2 SH2B ADAPTOR PROTEIN 1 SH2B1 rs4788102   28780899 NT_010393.15:g.20186477G > A 98.27 99.77 0.224 0.204 0.890/0.466
18q22 MELANOCORTIN 4 RECEPTOR MC4R rs17782313   56002077 NT_025028.13:g.5641943T > C 98.66 100 0.455 0.464 0.215/0.382
18q11-q12 NIEMANN-PICK DISEASE, TYPE C1 NPC1 rs1805081   19394430 NM_000271.3:c.644A > G (p.H215R) 98.93 99.65 0.343 0.376 0.012/0.017
19q13.11 POTASSIUM CHANNEL TETRAMERISATION KCTD15 rs11084753   39013977 NT_011109.15:g.6590355A > G 97.93 99.65 0.428 0.390 0.184/0.336
20q11.23-q12 CATENIN, BETA LIKE 1 CTNNBL1 rs6013029   35832994 NM_030877.3:c.750 + 3134G > T 98.27 99.88 0.267 0.283 0.574/0.482
Xq24 5-HYDROXYTRYPTAMINE RECEPTOR 2C HTR2C rs3813929   113724776 NT_028405.11:g.250852C > T 98.47 99.88 0.434 0.399 0.168/0.292
  1. HGN: Human genome nomenclature; SNP: single nucleotide polymorphism; CHR position: chromosomal position; HGVS: human genome variation society; Gen%: genotyping call rate; MAF: minor allele frequency.