BMI | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
Gene | SNP | A1 | MAF | Population | Prior statistical power | N* | Beta | Standard error | STAT** | P |
FTO | rs9939609* | A | 0.398 | PIZARRA | 32.77 | 848 | 0.875 | 0.23 | 3.79 | 0.0001573 |
0.435 | HORTEGA | 66.65 | 1345 | 0.1348 | 0.15 | 0.90 | 0.368 | |||
0.420 | POOLED | 77.88 | 2215 | 0.2976 | 0.13 | 2.19 | 0.0287 | |||
rs8044769 | T | 0.463 | PIZARRA | 30.96 | 848 | −0.582 | 0.23 | −2.54 | 0.0112 | |
0.455 | HORTEGA | 62.61 | 1331 | −0.1019 | 0.15 | −0.68 | 0.495 | |||
0.458 | POOLED | 73.98 | 2198 | −0.257 | 0.13 | −1.90 | 0.0571 | |||
rs7190492 | A | 0.328 | PIZARRA | 5.06 | 845 | −0.559 | 0.23 | −2.34 | 0.0192 | |
0.337 | HORTEGA | 5.16 | 1346 | 0.2065 | 0.16 | 1.29 | 0.195 | |||
0.333 | POOLED | 5.21 | 2213 | −0.07336 | 0.14 | −0.51 | 0.6076 | |||
rs6499640 | G | 0.376 | PIZARRA | 5.01 | 847 | 0.336 | 0.23 | 1.43 | 0.1511 | |
0.381 | HORTEGA | 5.02 | 1347 | 0.09312 | 0.15 | 0.60 | 0.543 | |||
0.379 | POOLED | 5.02 | 2216 | 0.2335 | 0.13 | 1.69 | 0.0911 | |||
MC4R | rs17782313* | C | 0.199 | PIZARRA | 9.69 | 848 | 0.575 | 0.28 | 1.98 | 0.0478 |
0.191 | HORTEGA | 16.33 | 1348 | 0.1167 | 0.19 | 0.60 | 0.544 | |||
0.195 | POOLED | 20.23 | 2218 | 0.3111 | 0.17 | 1.80 | 0.0716 | |||
MTCH2 | rs10838738 | G | 0.352 | PIZARRA | 5.80 | 845 | 0.453 | 0.24 | 1.88 | 0.0603 |
0.353 | HORTEGA | 6.98 | 1348 | 0.0972 | 0.15 | 0.62 | 0.536 | |||
0.353 | POOLED | 7.61 | 2215 | 0.1698 | 0.14 | 1.19 | 0.2318 | |||
NEGR1 | rs3101336 | A | 0.375 | PIZARRA | 7.89 | 848 | −0.084 | 0.24 | −0.34 | 0.7277 |
0.343 | HORTEGA | 11.89 | 1348 | −0.403 | 0.15 | −2.64 | 0.0083 | |||
0.355 | POOLED | 14.23 | 2210 | −0.1586 | 0.14 | −1.13 | 0.2561 | |||
ATXN2L | rs8049439 | C | 0.375 | PIZARRA | 8.87 | 848 | −0.139 | 0.23 | −0.58 | 0.5576 |
0.338 | HORTEGA | 14.15 | 1344 | 0.3292 | 0.15 | 2.13 | 0.0331 | |||
0.353 | POOLED | 17.35 | 2209 | 0.1715 | 0.14 | 1.22 | 0.2198 | |||
HTR2C | rs3813929 | T | 0.157 | PIZARRA | 10.16 | 847 | −0.406 | 0.35 | −1.16 | 0.2455 |
0.182 | HORTEGA | 19.46 | 1342 | −0.4365 | 0.23 | −1.89 | 0.0577 | |||
0.172 | POOLED | 23.29 | 2211 | −0.5551 | 0.20 | −2.68 | 0.0073 | |||
ADRB2 | rs12654778 | A | 0.388 | PIZARRA | 3 5.35 | 848 | 0.271 | 0.23 | 1.16 | 0.2452 |
0.380 | HORTEGA | 69.22 | 1347 | −0.1452 | 0.15 | −0.95 | 0.339 | |||
0.382 | POOLED | 80.65 | 2217 | 0.01463 | 0.13 | 0.10 | 0.9152 | |||
SEC16B | rs10913469 | C | 0.142 | PIZARRA | 9.33 | 848 | 0.392 | 0.32 | 1.21 | 0.2266 |
0.152 | HORTEGA | 16.43 | 1347 | −0.1609 | 0.20 | −0.78 | 0.432 | |||
0.148 | POOLED | 19.78 | 2216 | 0.00939 | 0.18 | 0.05 | 0.96 | |||
TMEM18 | rs4854344 | G | 0.172 | PIZARRA | 15.26 | 847 | −0.198 | 0.30 | −0.64 | 0.5173 |
0.169 | HORTEGA | 30.08 | 1348 | −0.3012 | 0.20 | −1.48 | 0.138 | |||
0.170 | POOLED | 37.86 | 2217 | −0.243 | 0.18 | −1.33 | 0.1815 | |||
INSIG2 | rs7566605 | C | 0.327 | PIZARRA | 13.68 | 846 | 0.101 | 0.24 | 0.41 | 0.676 |
0.321 | HORTEGA | 26.42 | 1348 | −0.0301 | 0.16 | −0.18 | 0.8514 | |||
0.322 | POOLED | 33.12 | 2216 | 0.1152 | 0.14 | 0.79 | 0.4265 | |||
ADIPOQ | rs17300539 | A | 0.126 | PIZARRA | 7.59 | 844 | −0.072 | 0.33 | −0.21 | 0.8298 |
0.118 | HORTEGA | 11.08 | 1348 | 0.1146 | 0.22 | 0.51 | 0.6082 | |||
0.120 | POOLED | 13.15 | 2214 | 0.0818 | 0.20 | 0.40 | 0.6838 | |||
rs3774261 | A | 0.495 | PIZARRA | 10.96 | 844 | −0.036 | 0.22 | −0.16 | 0.8727 | |
0.461 | HORTEGA | 19.84 | 1346 | −0.0549 | 0.15 | −0.36 | 0.7138 | |||
0.473 | POOLED | 26.42 | 2210 | 0.0609 | 0.13 | 0.45 | 0.6503 | |||
ETV5 | rs7647305 | T | 0.205 | PIZARRA | 10.76 | 838 | 0.022 | 0.28 | 0.079 | 0.9364 |
0.215 | HORTEGA | 19.82 | 1325 | 0.2402 | 0.18 | 1.30 | 0.1927 | |||
0.213 | POOLED | 24.39 | 2175 | 0.2106 | 0.16 | 1.26 | 0.2077 | |||
GNPDA2 | rs10938397 | G | 0.440 | PIZARRA | 11.60 | 848 | −0.338 | 0.22 | −1.52 | 0.1278 |
0.455 | HORTEGA | 21.56 | 1348 | −0.048 | 0.15 | −0.32 | 0.7492 | |||
0.449 | POOLED | 26.80 | 2218 | −0.1687 | 0.13 | −1.26 | 0.2078 | |||
PRL | rs4712652 | A | 0.453 | PIZARRA | 5.28 | 828 | 0.203 | 0.23 | 0.87 | 0.3846 |
G | 0.487 | HORTEGA | 5.69 | 1326 | 0.0367 | 0.15 | 0.24 | 0.8056 | ||
A | 0.489 | POOLED | 5.91 | 2175 | −0.115 | 0.13 | −0.84 | 0.3976 | ||
PTER | rs10508503 | T | 0.093 | PIZARRA | 5.10 | 841 | −0.119 | 0.39 | −0.30 | 0.7617 |
0.112 | HORTEGA | 5.27 | 1315 | −0.279 | 0.23 | −1.21 | 0.2238 | |||
0.105 | POOLED | 5.34 | 2174 | −0.3695 | 0.21 | −1.71 | 0.0866 | |||
BDNF | rs925946 | T | 0.282 | PIZARRA | 10.40 | 848 | 0.128 | 0.24 | 0.51 | 0.6046 |
0.266 | HORTEGA | 17.97 | 1348 | −0.071 | 0.16 | −0.44 | 0.6578 | |||
0.272 | POOLED | 22.37 | 2215 | 0.0795 | 0.14 | 0.54 | 0.5855 | |||
rs10501087 | C | 0.253 | PIZARRA | 10.01 | 845 | 0.033 | 0.26 | 0.12 | 0.8988 | |
0.231 | HORTEGA | 16.77 | 1348 | 0.0875 | 0.17 | 0.49 | 0.6231 | |||
0.240 | POOLED | 20.96 | 2214 | 0.1472 | 0.15 | 0.93 | 0.3493 | |||
FAIM2 | rs7138803 | A | 0.352 | PIZARRA | 7.38 | 844 | 0.155 | 0.24 | 0.65 | 0.5159 |
0.352 | HORTEGA | 10.92 | 1348 | −0.0643 | 0.15 | −0.42 | 0.675 | |||
0.351 | POOLED | 12.81 | 2214 | 0.0513 | 0.14 | 0.36 | 0.7129 | |||
MAF | rs1424233 | A | 0.483 | PIZARRA | 5.29 | 846 | −0.192 | 0.23 | −0.83 | 0.4074 |
G | 0.499 | HORTEGA | 5.70 | 1348 | 0.2336 | 0.14 | 1.57 | 0.1158 | ||
A | 0.495 | POOLED | 5.92 | 2216 | −0.2422 | 0.13 | −1.79 | 0.0725 | ||
NPC1 | rs1805081 | G | 0.329 | PIZARRA | 5.25 | 845 | −0.014 | 0.24 | −0.05 | 0.9553 |
0.352 | HORTEGA | 5.64 | 1345 | 0.0046 | 0.15 | 0.03 | 0.9758 | |||
0.344 | POOLED | 5.83 | 2212 | −0.0463 | 0.14 | −0.32 | 0.7432 | |||
KCTD15 | rs11084753 | A | 0.395 | PIZARRA | 5.62 | 846 | 0.093 | 0.23 | 0.39 | 0.6897 |
0.352 | HORTEGA | 6.44 | 1343 | −0.1562 | 0.15 | −1.01 | 0.31 | |||
0.367 | POOLED | 6.94 | 2210 | 0.0573 | 0.13 | 0.41 | 0.6781 | |||
CTNNBL1 | rs6013029 | T | 0.091 | PIZARRA | 5.79 | 847 | 0.014 | 0.39 | 0.036 | 0.9708 |
0.066 | HORTEGA | 6.44 | 1348 | −0.1522 | 0.30 | −0.50 | 0.6133 | |||
0.076 | POOLED | 7.16 | 2216 | 0.1139 | 0.25 | 0.44 | 0.6547 |