BMC Genomic Data

Table 4 Meta-analysis for the association of BMI with individual SNPs, for Pizarra and Hortega studies, and level of statistical heterogeneity for each SNP

From: Impact of obesity-related genes in Spanish population

						BMI
CHR	Gene	SNP	A1	P	P(R)	Beta	Beta(R)	Q	I
16	FTO	rs9939609	A	0.004768	0.1902	0.3544	0.4843	0.0071	86.22
		rs8044769	T	0.05001	0.1921	−0.245	−0.3108	0.0788	67.64
		rs7190492	A	0.8216	0.6838	−0.0299	−0.1556	0.0076	85.97
		rs6499640	G	0.1948	0.1948	0.1659	0.1659	0.3853	0
18	MC4R	rs17782313	C	0.1092	0.1872	0.2563	0.2941	0.1879	42.34
11	MTCH2	rs10838738	G	0.1222	0.1837	0.2031	0.2281	0.2157	34.75
1	NEGR1	rs3101336	A	0.0154	0.04555	−0.3124	−0.2989	0.2647	19.6
16	ATXN2L	rs8049439	C	0.1431	0.5759	0.1893	0.1295	0.0975	63.58
23	HTR2C	rs3813929	T	0.02603	0.02603	−0.4272	−0.4272	0.9414	0
5	ADRB2	rs12654778	A	0.8699	0.9013	−0.0208	0.0254	0.1347	55.32
1	SEC16B	rs10913469	C	0.9855	0.8286	−0.0031	0.0586	0.149	51.97
2	TMEM18	rs4854344	G	0.1106	0.1106	−0.2701	−0.2701	0.781	0
	INSIG2	rs7566605	C	0.9423	0.9423	0.0097	0.0097	0.652	0
3	ADIPOQ	rs17300539	A	0.758	0.758	0.0573	0.0573	0.6433	0
		rs3774261	A	0.6931	0.6931	−0.0494	−0.0494	0.9466	0
	ETV5	rs7647305	T	0.2549	0.2549	0.1763	0.1763	0.5226	0
4	GNPDA2	rs10938397	G	0.2632	0.2853	−0.1393	−0.1474	0.2784	14.87
10	PTER	rs10508503	T	0.2284	0.2284	−0.2387	−0.2387	0.7263	0
11	BDNF	rs925946	T	0.9293	0.9293	−0.012	−0.012	0.4992	0
		rs10501087	C	0.633	0.633	0.0701	0.0701	0.8626	0
12	FAIM2	rs7138803	A	0.9989	0.9989	−0.0002	−0.0002	0.4393	0
18	NPC1	rs1805081	G	0.9971	0.9971	−0.0005	−0.0005	0.9492	0
19	KCTD15	rs11084753	A	0.5295	0.5295	−0.0808	−0.0808	0.3724	0
20	CTNNBL1	rs6013029	T	0.7034	0.7034	−0.0914	−0.0914	0.738	0

CHR: Chromosome code; SNP: SNP identifier; A1: Minor allele code; P: Fixed-effects meta-analysis p-value; P(R): Random-effects meta-analysis p-value; BETA: Fixed-effects BETA estimate; BETA(R): Random-effects BETA estimate; Q: p-value for Cochrane’s Q statistic; I: I²heterogeneity index (0-100).

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