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Table 4 Meta-analysis for the association of BMI with individual SNPs, for Pizarra and Hortega studies, and level of statistical heterogeneity for each SNP

From: Impact of obesity-related genes in Spanish population

       BMI
CHR Gene SNP A1 P P(R) Beta Beta(R) Q I
16 FTO rs9939609 A 0.004768 0.1902 0.3544 0.4843 0.0071 86.22
   rs8044769 T 0.05001 0.1921 −0.245 −0.3108 0.0788 67.64
   rs7190492 A 0.8216 0.6838 −0.0299 −0.1556 0.0076 85.97
   rs6499640 G 0.1948 0.1948 0.1659 0.1659 0.3853 0
18 MC4R rs17782313 C 0.1092 0.1872 0.2563 0.2941 0.1879 42.34
11 MTCH2 rs10838738 G 0.1222 0.1837 0.2031 0.2281 0.2157 34.75
1 NEGR1 rs3101336 A 0.0154 0.04555 −0.3124 −0.2989 0.2647 19.6
16 ATXN2L rs8049439 C 0.1431 0.5759 0.1893 0.1295 0.0975 63.58
23 HTR2C rs3813929 T 0.02603 0.02603 −0.4272 −0.4272 0.9414 0
5 ADRB2 rs12654778 A 0.8699 0.9013 −0.0208 0.0254 0.1347 55.32
1 SEC16B rs10913469 C 0.9855 0.8286 −0.0031 0.0586 0.149 51.97
2 TMEM18 rs4854344 G 0.1106 0.1106 −0.2701 −0.2701 0.781 0
  INSIG2 rs7566605 C 0.9423 0.9423 0.0097 0.0097 0.652 0
3 ADIPOQ rs17300539 A 0.758 0.758 0.0573 0.0573 0.6433 0
   rs3774261 A 0.6931 0.6931 −0.0494 −0.0494 0.9466 0
  ETV5 rs7647305 T 0.2549 0.2549 0.1763 0.1763 0.5226 0
4 GNPDA2 rs10938397 G 0.2632 0.2853 −0.1393 −0.1474 0.2784 14.87
10 PTER rs10508503 T 0.2284 0.2284 −0.2387 −0.2387 0.7263 0
11 BDNF rs925946 T 0.9293 0.9293 −0.012 −0.012 0.4992 0
   rs10501087 C 0.633 0.633 0.0701 0.0701 0.8626 0
12 FAIM2 rs7138803 A 0.9989 0.9989 −0.0002 −0.0002 0.4393 0
18 NPC1 rs1805081 G 0.9971 0.9971 −0.0005 −0.0005 0.9492 0
19 KCTD15 rs11084753 A 0.5295 0.5295 −0.0808 −0.0808 0.3724 0
20 CTNNBL1 rs6013029 T 0.7034 0.7034 −0.0914 −0.0914 0.738 0
  1. CHR: Chromosome code; SNP: SNP identifier; A1: Minor allele code; P: Fixed-effects meta-analysis p-value; P(R): Random-effects meta-analysis p-value; BETA: Fixed-effects BETA estimate; BETA(R): Random-effects BETA estimate; Q: p-value for Cochrane’s Q statistic; I: I2heterogeneity index (0-100).