Table 4 Positional candidate genes (PCG) within 1-Mb SNP window (SNPW) and their putative functions
From: Genome-wide association study of infectious bovine keratoconjunctivitis in Angus cattle
Chromosome | SNPW | PCG | Gene ontology |
|---|---|---|---|
2 | 19.11 - 19.97 | AGPS | It encodes a protein that catalyzes the step of lipid biosynthesis |
| Â | Â | Â | and the removal of long chain acid anion |
| Â | Â | NFE2L2 | It encodes a transcription factor which is a member of a small |
| Â | Â | Â | family of basic Leucine (bZIP) proteins |
2 | 22.09 - 22.77 | WIPF1 | It encodes a protein that plays an important role in the organization |
| Â | Â | Â | of the actin cytoskeleton |
| Â | Â | OLA1 | It hydrolyzes ATP and can hydrolyze GTP with lower efficiency |
| Â | Â | SP3 | regulates transcription by binding consensus GC and GT- box |
| Â | Â | Â | elements in target genes |
12 | 53.01 - 53.99 | SCEL | It encodes a tissue-specific basic helix-loop-helix (bHLH) protein |
| Â | Â | Â | with a pivotal role in hemopoises |
| Â | Â | EDNRB | it mediates actin by association with G-Protein that activates |
| Â | Â | Â | a phosphaidylinositol-calcium second messenger system |
13 | 14.36 - 14.92 | VAMP7 | It encodes a transmembrane protein that is a member of soluble |
| Â | Â | Â | N-ethylmeleimide-sensitive factor attachment protein receptor |
| Â | Â | Â | (SNARE) family |
21 | 19.00 - 19.98 | NTRK3 | It encodes a member of a neurotrophic tyrosine receptor kinase family |
| Â | Â | MIR1179 | It involved in post transcriptional regulation of gene expression |
| Â | Â | MIR7-1 | It involved in post transcriptional regulation of gene expression |