Figure 5
From: Carriers of a novel frame-shift insertion in WNT16a possess elevatedpancreatic expression of TCF7L2
Gene expression study of TCF7L2 in the same 27 pancreatic tissues usedto determine the expression of Wnt16a by real-time PCR analysis.Figure 5A shows a significant elevationof TCF7L2 mRNA levels among CCCA insertion carriers and a very lowexpression of TCF7L2 mRNA was observed in non-carriers (p= 0.003).Figure 5B shows that within CCCAinsertion carriers, the expression of TCF7L2 mRNA in pancreas waselevated among diabetics compared to non-diabetic controls.