Figure 6
From: Carriers of a novel frame-shift insertion in WNT16a possess elevatedpancreatic expression of TCF7L2
Stratification of TCF7L2 mRNA quantitation by TCF7L2 genotypes of rs7903146 among Wnt16a insertion carriersand non-carriers. The at-risk ‘T’ allele carriers ofTCF7L2 with CT+TT genotypes showed a 8.7-fold increase inthe expression of TCF7L2 compared to CC genotypes. Note that thisincrease was only observed in Wnt16a (CCCA) insertion carriersand not in the non-carriers.