Figure 8
From: Carriers of a novel frame-shift insertion in WNT16a possess elevatedpancreatic expression of TCF7L2
Immunoperoxidase staining of 5 micron thick histological sections ofparaffin-embedded pancreatic tissues. The sections wereprocessed for immunohistochemistry using the HiDef detection HRPMouse/Rabbit polymer system as described in detail under methods. TheCCCA insertion carriers revealed a higher expression of Wnt16, showingstaining score from +1 to +3 among insertion carriers versus negativestaining in non-carriers, which showed staining scores from 0 to +1. Thescoring intensity was not different among diabetic andnon-diabetics.