Investigation of gene-by-sex interactions for lipid traits in diverse populations from the population architecture using genomics and epidemiology study

Table 1 Characteristics of PAGE study populations

	EAGLE*	MEC	WHI	CALiCo
				ARIC	CARDIA	CHS	SHS
Type of Study	Cross-sectional	Nested Case Control	Cohort and Clinical Trials	Longitudinal	Longitudinal	Longitudinal	Longitudinal
Focus of Cohort	N/A	Cancer	Women’s Health	Cardiovascular Disease	Cardiovascular Disease	Cardiovascular Disease	Cardiovascular Disease
Years Collected	1991-1994, 1999-2002	1993-1996	1993-1998	1987-2007	1986-2006	1989-1999	1988-present
Median Age	43	67	63	54	25	73	47
Age Range	18-90	48-86	50-79	44-66	18-35	64-96	14-93
% Women	54	36	100	57	56	62	59.3
Sample sizes:
European Americans	3,909^†	317	4,688	11,178	2,134	2,787	--
African Americans	1,896	552	1,840	3,770	2,035	550	--
American Indians	--	--	113	--	--	--	6,021
Mexican Americans	2,361	299	762	--	--	--	--

*Abbreviations: Epidemiologic Architecture for Genes Linked to Environment (EAGLE); Multiethnic Cohort (MEC); Women’s Health Initiative (WHI); Causal Variants Across the Life Course (CALiCo); Atherosclerosis Risk in Communities (ARIC); Coronary Artery Risk Development in Young Adults (CARDIA); Cardiovascular Health Study (CHS); Strong Heart Study (SHS).
†The numbers shown are the maximum for any of the three phenotypes (LDL, HDL, or lnTG).

ISSN: 2730-6844