A network of all CYP3A5 haplotypes inferred for Ethiopians and Coriell populations. Networks assume single mutational steps. Haplotypes are colored according to the haplogroup to which they belong; haplotypes which are defined by the CYP3A5*3 allele are shown in red; those defined by CYP3A5*1 in yellow; CYP3A5*7 in green; CYP3A5*6 in blue and CYP3A5*3/*6 recombinant haplotypes are shown in purple. The size of each haplotype is proportional to its frequency in the global database. Additional file 4 Figure S3a contains information on the exact composition of each coded haplotype.