Genetic background (DDD/Sgn versus C57BL/6J) strongly influences postnatal growth of male mice carrying the A y allele at the agouti locus: identification of quantitative trait loci associated with diabetes and body weight loss

Table 6 Single QTL scans for body weight at 25 weeks in combined BC mice using the agouti genotype as a covariate

Chromosome	LOD scores (peak position, cM)
Chromosome	*Agouti*as an additive covariate (LOD_a)^a	*Agouti*as an interactive covariate (LOD_f)^b	LOD_i(LOD_f-LOD_a)^c
4	None	3.52 (61)	2.27 (49)

Only significant QTLs are listed.
^aSignificant threshold LOD score was 2.57.
^bSignificant threshold LOD score was 3.28.
^cLOD_i is the difference between the LOD score with agouti as an interactive covariate (LOD_f) and the LOD score with agouti as an additive covariate (LOD_a). This derives from a test of the QTL × agouti interaction. Significant threshold LOD score was 1.91.

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