Genetic background (DDD/Sgn versus C57BL/6J) strongly influences postnatal growth of male mice carrying the A y allele at the agouti locus: identification of quantitative trait loci associated with diabetes and body weight loss

Table 9 Comparison of phenotypes between two groups of BC A ^y males clustered by the partition method

Phenotypes at 25 weeks	Mean ± SE values (95% confident interval)
	Abnormal mice (PGLC ≥ 715)^b	Normal mice (PGLC < 715)
	(n = 9)	(n = 91)
Body weight (g)	41.2 ± 0.70^c	50.17 ± 0.47
Body weight (g)	(39.59–42.83)	(49.23–51.12)
BMI	3.90 ± 0.10^c	4.54 ± 0.03
BMI	(3.70–4.10)	(4.48–4.60)
Blood glucose (mg/dl)^a	592.2 ± 4.6^c	303.7 ± 13.7
Blood glucose (mg/dl)^a	(581.5–602.9)	(276.6–330.8)
Plasma glucose (mg/dl)	754.8 ± 15.3^c	394.9 ± 16.9
Plasma glucose (mg/dl)	(719.6-790.0)	(361.3–428.5)
Total-cholesterol (mg/dl)	133.4 ± 14.7	156.0 ± 4.6
Total-cholesterol (mg/dl)	(104.3–162.6)	(146.8–165.2)
Triglyceride (mg/dl)	734.1 ± 81.7	610.9 ± 25.7
Triglyceride (mg/dl)	(571.9–896.3)	(560.0–661.9)
HMW adiponectin (μg/ml)	2.61 ± 0.13^c	3.93 ± 0.14
HMW adiponectin (μg/ml)	(2.29–2.92)	(3.66–4.21)

^aSeven mice had blood glucose levels that exceeded the upper limit of the measuring method (600 mg/dl). Therefore, mean ± SE values were calculated by assuming that their blood glucose levels were 600 mg/dl.
^bPGLC indicates plasma glucose levels.
^cValues are significantly different between abnormal mice and normal mice.

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