Table 1 Gene Ontology (GO) categories enriched for coexpressed gene modules that correlated with phenotypic traits
Tissues (gene module no.) | Correlated trait | Functional category | Term description | Pvalue | Involved gene no. |
|---|---|---|---|---|---|
LDM (2) | Apo-A1 | GO-BP | Metabolic process | 1.06 × 10-7 | 139 |
GO-BP | Primary metabolic process | 4.55 × 10-8 | 127 | ||
GO-BP | Protein metabolic process | 5.03 × 10-4 | 94 | ||
GO-BP | Carbohydrate metabolic process | 0.028 | 82 | ||
GO-BP | Protein modification process | 0.016 | 73 | ||
GO-BP | Protein amino acid phosphorylation | 0.016 | 65 | ||
LDM (4) | LDH | GO-BP | Cellular metabolic process | 5.22 × 10-6 | 100 |
GO-BP | Metabolic process | 5.58 × 10-5 | 105 | ||
GO-BP | Cellular process | 2.47 × 10-4 | 128 | ||
GO-BP | Cellular nitrogen compound metabolic process | 0.048 | 60 | ||
GO-BP | Primary metabolic process | 0.016 | 93 | ||
PMM (2) | OX-B | GO-BP | Immune system process | 2.12 × 10-5 | 29 |
GO-BP | Inflammatory response | 0.001 | 16 | ||
GO-BP | Response to external stimulus | 0.001 | 26 | ||
GO-BP | Response to wounding | 0.001 | 20 | ||
GO-BP | Immune response | 0.001 | 22 | ||
GO-BP | Regulation of immune system process | 0.002 | 16 | ||
GO-BP | Regulation of response to stimulus | 0.004 | 17 | ||
GO-BP | Positive regulation of immune system process | 0.006 | 12 | ||
GO-BP | Regulation of immune response | 0.012 | 12 | ||
GO-BP | Lymphocyte activation | 0.021 | 11 | ||
GO-BP | Cell activation | 0.031 | 12 | ||
GO-BP | Leukocyte activation | 0.033 | 11 | ||
GO-BP | Positive regulation of lymphocyte activation | 0.049 | 8 | ||
GO-MF | Receptor binding | 2.19 × 10-5 | 30 | ||
PMM (4) | OXR | GO-BP | Immune response | 0.019 | 9 |
GO-BP | Immune system process | 1.79 × 10-6 | 16 | ||
GO-BP | Cellular defense response | 0.027 | 6 | ||
GO-BP | Response to stimulus | 4.87 × 10-4 | 12 | ||
|  |  | GO-BP | Cell-matrix adhesion | 2.24 × 10-3 | 10 |