Computational cloning of drug target genes of a parasitic nematode, Oesophagostomum dentatum

BMC Genomic Data

Table 2 Target gene identification and comparison

Gene ID	Max HSP length (DNA)		Max Contig length (DNA)		Max Contig length (AA)		Length (AA)	Final vs C. elegansprotein		*O. dentatum*
	Initial	Final	Initial	Final	Initial	Final	*C. elegans*	% ID	% full length	Acc #
Levamisole target genes (nAChR subunits)
lev-1	1401	1401	1580	1612	467	477	472	91	100	GACS01000001
lev-8	255	255	269	269	85	89	531	85	17	GACS01000002
unc-29	480	576	482	614	160	204	493	88	41	GACS01000003
unc-38	1473	1455	1607	1631	491	507	511	72	100	GACS01000004
unc-63	576	1248	578	1770	192	417	502	82	82	GACS01000005
Macrocyclic lactone, benzimidazole target genes
avr-14	390	1299	629	1485	130	464	416	52	100	GACS01000006
avr-15	291	1242	560	1531	97	447	478	44	100	GACS01000007
ben-1_1	453	1308	453	1436	151	448	444	94	100	GACS01000008
ben-1_2	453	1317	453	1751	151	448	444	95	100	GACS01000009
glc-2	939	1215	994	1389	313	424	434	72	100	GACS01000010
glc-3	1383	1383	1724	2048	461	531	484	58	100	GACS01000011
glc-4	1428	1521	1628	1628	476	508	500	77	100	GACS01000012

Best initial high scoring pair (HSP) and contig lengths correspond to the longest HSP from the initial read assemblies (see bold values from Table 1) and the contig from which that HSP derives. “% full length” represents the percent of the comparator C. elegans protein that is represented within the final contig. “% ID” represents the percent identity as determined by pairwise alignment.

ISSN: 2730-6844