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Table 4 The accuracy and precision assessment

From: Evaluation of a target region capture sequencing platform using monogenic diabetes as a study-model

Filtered conditions SOAPsnp score ≥ 20; Depth ≥ 20;
Percentage of reads supporting ≥ 28%
Target covered: 4944470 bp
Total number of SNPs: 9572
Total number of target SNPs: 6127
YH target in dbSNP: 6463
True positive (TP ratio): 5847 (90.96%)
True negative (TN ratio): 4937762 (99.99%)
False negative (FN ratio): 581 (9.04%)
False positive (FP ratio): 280 (0.006%)
Accuracy (%)((TP + TN)/(TP + FN + TN + FP)): 99.98
Precision (%)(TP/(TP + FN)): 95.43
  1. The assessment is calculated based on qualified SNPs filtered by SOAPsnp score, depth, and supporting reads ratio.