The count of CNV components (y-axis) delineated via MinimumDistance in the cleft lip/palate trios (green) and control trios (yellow), as a function of genomic location (x-axis) near 7p14.1, plus the corresponding numbers delineated via PennCNV in the cleft lip/palate trios (red) and control trios (blue). Segments are defined as collections of probes where CNV composition does not change in the combined trio sets. Short lines thus represent small differences in width among de novo deletions. The most significant association was observed in a sub-region where MinimumDistance (PennCNV) identified 10 (20) cleft lip/palate subjects with a de novo deletion, and none (one) in the control trios. The nearest gene is the T cell receptor gamma alternate reading frame protein TARP, about 20 kb away from the de novo deletions.