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Table 3 Interaction between vitamin D receptor ( VDR ) and retinoid X receptor-gamma ( RXRG ) polymorphisms in the replication cohorts (Northern Finland Birth Cohort 1966 and Twins UK)

From: Interaction between allelic variations in vitamin D receptor and retinoid X receptor genes on metabolic traits

Outcome VDR RXRG Northern Finland Birth Cohort 1966 (NFBC66) Twins UK Meta-analysis of the results from NFBC66 and Twins UK
  SNP SNP         
    N in analysis Interaction Beta ± SE Pinteraction N in analysis Interaction Beta ± SE Pinteraction Interaction Beta ± SE Unadjusted Pinteraction(Adjusted Pinteraction*)
Low density lipoprotein cholesterol rs3847987 rs283695 5,007 −0.03 ± 0.03 0.26 1,555 −0.08 ± 0.08 0.31 −0.04 ± 0.03 0.16
rs11574143 rs283695 4,990 −0.02 ± 0.03 0.52 1,528 −0.03 ± 0.08 0.75 −0.02 ± 0.03 0.48
Serum triglycerides rs11574143 rs17429123 5,155 0.01 ± 0.03 0.74 1,686 0.09 ± 0.06 0.13 0.03 ± 0.03 0.32
rs11574143 rs10918172 5,131 0.03 ± 0.03 0.28 1,725 0.05 ± 0.05 0.37 0.04 ± 0.03 0.16
rs3847987 rs17429123 5,172 0.03 ± 0.03 0.28 1,730 0.08 ± 0.05 0.09 0.05 ± 0.02 0.08
rs3847987 rs10918172 5,148 0.05 ± 0.03 0.07 1,767 0.07 ± 0.05 0.14 0.06 ± 0.03 0.02 (0.17)
rs739837, rs2238136 rs1273959 5,204 −0.002 ± 0.03 0.95 1,883 0.01 ± 0.04 0.79 0.003 ± 0.03 0.91
Waist hip ratio rs2283342 rs157872 4,707 0.002 ± 0.003 0.53 3,376 −0.002 ± 0.004 0.62 0.001 ± 0.002 0.78
  1. *Bonferroni correction applied to Pinteraction values.